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Protein Domain : IPR022689

Name  Iron dependent repressor, diptheria toxin type Short Name  Fe_dep_repressor_HTH_DtxR
Type  Domain Description  The diphtheria toxin repressor protein (DTXR) is a member of this group []. In Corynebacterium diphtheriaewhere it has been studied in some detail this protein actsas an iron-binding repressor of dipheteria toxin gene expression and may serve as a global regulator of gene expression. The N terminus may be involved in iron binding andmay associate with the Tox operator. Binding of DTXR to Tox operator requires a divalentmetal ion such as cobalt, ferric, manganese and nickel whereas zinc shows weak activation [].

Publication Counts Displayer

0 Child Features

3 Contains

DB identifier Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain
IPR022687 Iron dependent repressor, N-terminal Fe_dep_repressor_HTH_DtxR_N Domain
IPR001367 Iron dependent repressor-like, metal binding and dimerisation domain Fe_dep_repressor Domain

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
SM00529 SMART IPR022689

2 Data Sets

Name URL
InterPro data set  
InterPro GO Annotation data set  

0 Found In

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Iron dependent repressor, diptheria toxin type   GO:0003700 sequence-specific DNA binding transcription factor activity
Iron dependent repressor, diptheria toxin type   GO:0046914 transition metal ion binding
Iron dependent repressor, diptheria toxin type   GO:0006355 regulation of transcription, DNA-templated

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Iron dependent repressor, diptheria toxin type   GO:0003700 sequence-specific DNA binding transcription factor activity
Iron dependent repressor, diptheria toxin type   GO:0046914 transition metal ion binding
Iron dependent repressor, diptheria toxin type   GO:0006355 regulation of transcription, DNA-templated

0 Parent Features

0 Proteins