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Protein Domain : IPR015189

Name  Translation elongation factor SelB, winged helix, type 1 Short Name  Elong_fac_SelB-wing-hlx_typ-1
Type  Domain Description  This entry represents a domain with a winged helix-type fold, which consists of a closed 3-helical bundle with a right-handed twist, and a small beta-sheet wing []. Different winged helix domains share a common structure, but can differ in sequence. This entry is designated "type 1". The winged helix motif is involved in both DNA and RNA binding. In the elongation factor SelB, the winged helix domains recognise RNA, allowing the complex to wrap around the small ribosomal subunit. In bacteria, the incorporation of the amino acid selenocysteine into proteins requires elongation factor SelB, which binds both transfer RNA (tRNA) and mRNA. SelB binds to an mRNA hairpin formed by the selenocysteine insertion sequence (SECIS) with extremely high specificity [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Source . Name

Subject . Primary Identifier
PF09105 PFAM IPR015189

1 Data Sets

Name URL
InterPro data set  

2 Found In

DB identifier Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain
IPR004535 Translation elongation factor, selenocysteine-specific Transl_elong_SelB Family

0 GO Annotation

0 Ontology Annotations

0 Parent Features

0 Proteins