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Protein Domain : IPR015725

Name  Telokin/Myosin light chain kinase Short Name  Telokin/Myosin_light_ch_kin
Type  Family Description  Smooth muscle myosin light chain kinase is a Ser/Thr protein kinase, contains 1 fibronectin type-III domain and 9 Ig-like C2-type (immunoglobulin-like) domains (based on similarity to other like proteins). These kinases phosphorylate a specific serine in the N terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes, which allow selective transduction of calcium signals. In this reaction magnesium and calcium act as cofactors and the kinases are activated by phosphorylation on Tyr-478 (), (). Also included in this entry is telokin, an acidic protein identical to the C-terminal portion of myosin light chain kinase [].

Publication Counts Displayer

0 Child Features

10 Contains

DB identifier Name Short Name Type
IPR011009 Protein kinase-like domain Kinase-like_dom Domain
IPR000719 Protein kinase domain Prot_kinase_dom Domain
IPR017441 Protein kinase, ATP binding site Protein_kinase_ATP_BS Binding_site
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain Ser/Thr_dual-sp_kinase_dom Domain
IPR008271 Serine/threonine-protein kinase, active site Ser/Thr_kinase_AS Active_site
IPR013783 Immunoglobulin-like fold Ig-like_fold Domain
IPR007110 Immunoglobulin-like domain Ig-like_dom Domain
IPR013098 Immunoglobulin I-set Ig_I-set Domain
IPR003598 Immunoglobulin subtype 2 Ig_sub2 Domain
IPR003961 Fibronectin, type III Fibronectin_type3 Domain

1 Cross References

Source . Name

Subject . Primary Identifier
PTHR22964:SF44 PANTHER IPR015725

1 Data Sets

Name URL
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Name Short Name Type
IPR020675 Myosin light chain kinase-related Myosin_light_ch_kinase-rel Family

0 Proteins