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Protein Domain : IPR004620

Name  5,10-methylenetetrahydrofolate reductase Short Name  MTHF_reductase_bac
Type  Family Description  The enzyme activities methylenetetrahydrofolate reductase () and 5,10-methylenetetrahydrofolate reductase (FADH) () differ in that the former (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while the latter (assigned in many bacteria) is flexible with respect to the acceptor. Both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as one or the other, this family describes the subset of proteins found in bacteria, and currently designated 5,10-methylenetetrahydrofolate reductase. This protein is an FAD-containing flavoprotein.

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
TIGR00676 TIGRFAMs IPR004620

2 Data Sets

Name URL
InterPro data set  
InterPro GO Annotation data set  

0 Found In

4 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
5,10-methylenetetrahydrofolate reductase   GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
5,10-methylenetetrahydrofolate reductase   GO:0009086 methionine biosynthetic process
5,10-methylenetetrahydrofolate reductase   GO:0055114 oxidation-reduction process
5,10-methylenetetrahydrofolate reductase   GO:0005829 cytosol

4 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
5,10-methylenetetrahydrofolate reductase   GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
5,10-methylenetetrahydrofolate reductase   GO:0009086 methionine biosynthetic process
5,10-methylenetetrahydrofolate reductase   GO:0055114 oxidation-reduction process
5,10-methylenetetrahydrofolate reductase   GO:0005829 cytosol

1 Parent Features

DB identifier Name Short Name Type
IPR003171 Methylenetetrahydrofolate reductase Mehydrof_redctse Family

0 Proteins