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Protein Domain : IPR015707

Name  Beta-2-Microglobulin Short Name  B2Microglobulin
Type  Family Description  Beta-2-microglobulin constitutes the 12 kDa light chain of the class I major histocompatibility complex (MHC-I) on the surface of many cells, to which it is non-covalently associated. It is also found in the serum in a free form. Beta-2-microglobulin co-association with the MHC class I heavy chain is prerequisite for functional expression of the protein complex on the cell surface. Together these function in the presentation of nine amino acid peptides to the T-cell receptor of CD8-bearing T lymphocytes and killer inhibitory receptors on natural killer cells.

Publication Counts Displayer

0 Child Features

4 Contains

DB identifier Name Short Name Type
IPR013783 Immunoglobulin-like fold Ig-like_fold Domain
IPR007110 Immunoglobulin-like domain Ig-like_dom Domain
IPR003006 Immunoglobulin/major histocompatibility complex, conserved site Ig/MHC_CS Conserved_site
IPR003597 Immunoglobulin C1-set Ig_C1-set Domain

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PTHR19944:SF58 PANTHER IPR015707

2 Data Sets

Name URL
InterPro data set  
InterPro GO Annotation data set  

0 Found In

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Beta-2-Microglobulin   GO:0006955 immune response
Beta-2-Microglobulin   GO:0042612 MHC class I protein complex

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Beta-2-Microglobulin   GO:0006955 immune response
Beta-2-Microglobulin   GO:0042612 MHC class I protein complex

0 Parent Features

0 Proteins