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Pathway : 131559 CREB phosphorylation through the activation of Ras

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

7 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0003256 CG12559 rl rolled FlyBase D. melanogaster
FBgn0020386 CG1210 Pdk1 Phosphoinositide-dependent kinase 1 FlyBase D. melanogaster
FBgn0003079 CG2845 phl pole hole FlyBase D. melanogaster
FBgn0264607 CG18069 CaMKII Calcium/calmodulin-dependent protein kinase II FlyBase D. melanogaster
FBgn0265784 CG6103 CrebB Cyclic-AMP response element binding protein B FlyBase D. melanogaster
FBgn0003206 CG1167 Ras64B Ras oncogene at 64B FlyBase D. melanogaster
FBgn0262866 CG17596 S6kII Ribosomal protein S6 kinase II FlyBase D. melanogaster

9 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0099496 Q00168 Drosophila melanogaster
FBpp0073068 P04388 Drosophila melanogaster
FBpp0070385 P11346 Drosophila melanogaster
FBpp0112426 P40417 Drosophila melanogaster
FBpp0072366 Q9W0V1 Drosophila melanogaster
FBpp0077052 Q9VR61 Drosophila melanogaster
FBpp0074326 Q9VWW0 Drosophila melanogaster
Q86NP0_DROME Q86NP0 Drosophila melanogaster
Q24496_DROME Q24496 Drosophila melanogaster