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Pathway : 89434 Inhibition of TSC complex formation by PKB

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

3 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0005198 CG6975 gig gigas FlyBase D. melanogaster
FBgn0026317 CG6147 Tsc1 Tsc1 FlyBase D. melanogaster

15 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0083931 Q9VCC9 Drosophila melanogaster
FBpp0074588 Q9VW83 Drosophila melanogaster
H1ZYA5_DROME H1ZYA5 Drosophila melanogaster
H1ZYA3_DROME H1ZYA3 Drosophila melanogaster
H1ZYA6_DROME H1ZYA6 Drosophila melanogaster
Q9U9B0_DROME Q9U9B0 Drosophila melanogaster
Q9U9A9_DROME Q9U9A9 Drosophila melanogaster
H1ZYA8_DROME H1ZYA8 Drosophila melanogaster
H1ZYB0_DROME H1ZYB0 Drosophila melanogaster
Q7K0T0 Drosophila melanogaster
H1ZYC9 Drosophila melanogaster
H1ZYC5 Drosophila melanogaster
H1ZYD2 Drosophila melanogaster
H1ZYD3 Drosophila melanogaster