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Pathway : 145760 IRAK2 mediated activation of TAK1 complex

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

28 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0023423 CG3412 slmb supernumerary limbs FlyBase D. melanogaster
FBgn0260632 CG6667 dl dorsal FlyBase D. melanogaster
FBgn0024846 CG7393 p38b p38b FlyBase D. melanogaster
FBgn0010303 CG4353 hep hemipterous FlyBase D. melanogaster
FBgn0015765 CG5475 Mpk2 Mpk2 FlyBase D. melanogaster
FBgn0011274 CG6794 Dif Dorsal-related immunity factor FlyBase D. melanogaster
FBgn0026176 CG8881 skpB skpB FlyBase D. melanogaster
FBgn0000250 CG5848 cact cactus FlyBase D. melanogaster
FBgn0000229 CG5680 bsk basket FlyBase D. melanogaster
FBgn0024326 CG9738 Mkk4 MAP kinase kinase 4 FlyBase D. melanogaster
FBgn0001297 CG33956 kay kayak FlyBase D. melanogaster
FBgn0265464 CG10961 Traf6 TNF-receptor-associated factor 6 FlyBase D. melanogaster
FBgn0015509 CG1877 lin19 lin-19-like FlyBase D. melanogaster
FBgn0010441 CG5974 pll pelle FlyBase D. melanogaster
FBgn0001291 CG2275 Jra Jun-related antigen FlyBase D. melanogaster
FBgn0033402 CG2078 Myd88 Myd88 FlyBase D. melanogaster
FBgn0024222 CG4201 ird5 immune response deficient 5 FlyBase D. melanogaster
FBgn0014018 CG11992 Rel Relish FlyBase D. melanogaster
FBgn0025638 CG16982 Roc1a Roc1a FlyBase D. melanogaster
FBgn0003941 CG2960 RpL40 Ribosomal protein L40 FlyBase D. melanogaster
FBgn0086358 CG7417 Tab2 TAK1-associated binding protein 2 FlyBase D. melanogaster
FBgn0261524 CG12244 lic licorne FlyBase D. melanogaster
FBgn0026323 CG18492 Tak1 TGF-beta activated kinase 1 FlyBase D. melanogaster
FBgn0003943 CG11624 Ubi-p63E Ubiquitin-63E FlyBase D. melanogaster
FBgn0013987 CG3086 MAPk-Ak2 MAP kinase activated protein-kinase-2 FlyBase D. melanogaster
FBgn0041205 CG16910 key kenny FlyBase D. melanogaster
FBgn0002774 CG11680 mle maleless FlyBase D. melanogaster
FBgn0003942 CG5271 RpS27A Ribosomal protein S27A FlyBase D. melanogaster

39 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073578 Q23977 Drosophila melanogaster
FBpp0085704 Q6NQZ7 Drosophila melanogaster
FBpp0290793 P98149 Drosophila melanogaster
FBpp0073035 P0CG69 Drosophila melanogaster
FBpp0099941 A8MPH9 Drosophila melanogaster
FBpp0079606 P15357 Drosophila melanogaster
FBpp0070802 P49071 Drosophila melanogaster
FBpp0080560 P15330 Drosophila melanogaster
FBpp0073551 O62602 Drosophila melanogaster
FBpp0079676 P92208 Drosophila melanogaster
FBpp0081378 O61444 Drosophila melanogaster
FBpp0077011 Q9V3Q6 Drosophila melanogaster
FBpp0087921 Q24311 Drosophila melanogaster
FBpp0088375 Q94527 Drosophila melanogaster
FBpp0087499 P18289 Drosophila melanogaster
FBpp0080402 Q03017 Drosophila melanogaster
FBpp0083965 O62618 Drosophila melanogaster
FBpp0085367 P24785 Drosophila melanogaster
FBpp0087679 Q7K105 Drosophila melanogaster
FBpp0084549 Q05652 Drosophila melanogaster
FBpp0077159 P18101 Drosophila melanogaster
FBpp0087127 Q7KJ69 Drosophila melanogaster
FBpp0083434 Q9VDE3 Drosophila melanogaster
FBpp0080111 O61443 Drosophila melanogaster
FBpp0288515 P21525 Drosophila melanogaster
FBpp0071136 Q9W3I9 Drosophila melanogaster
FBpp0070117 Q9W5E1 Drosophila melanogaster
IKKB_DROME Q9VEZ5 Drosophila melanogaster
NEMO_DROME Q9GYV5 Drosophila melanogaster
Q9UAC4_DROME Q9UAC4 Drosophila melanogaster