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Pathway : 167467 DEx/H-box helicases activate type I IFN and inflammatory cytokines production

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

6 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0260632 CG6667 dl dorsal FlyBase D. melanogaster
FBgn0011274 CG6794 Dif Dorsal-related immunity factor FlyBase D. melanogaster
FBgn0033402 CG2078 Myd88 Myd88 FlyBase D. melanogaster
FBgn0014018 CG11992 Rel Relish FlyBase D. melanogaster
FBgn0032883 CG9323 CG9323 FlyBase D. melanogaster
FBgn0002774 CG11680 mle maleless FlyBase D. melanogaster

6 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0290793 P98149 Drosophila melanogaster
FBpp0080560 P15330 Drosophila melanogaster
FBpp0088375 Q94527 Drosophila melanogaster
FBpp0085367 P24785 Drosophila melanogaster
FBpp0080988 Q8SWT2 Drosophila melanogaster
FBpp0087679 Q7K105 Drosophila melanogaster