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Pathway : 105487 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

6 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0016984 CG9985 sktl skittles FlyBase D. melanogaster
FBgn0014011 CG8556 Rac2 Rac2 FlyBase D. melanogaster
FBgn0010333 CG2248 Rac1 Rac1 FlyBase D. melanogaster
FBgn0260442 CG6831 rhea rhea FlyBase D. melanogaster
FBgn0265082 CG44193 Cdep Chondrocyte-derived ezrin-like domain containing protein ortholog (H. sapiens) FlyBase D. melanogaster
FBgn0034789 CG3682 PIP5K59B PIP5K59B FlyBase D. melanogaster

15 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0072614 P40792 Drosophila melanogaster
FBpp0305023 P48554 Drosophila melanogaster
FBpp0071491 Q9W2R3 Drosophila melanogaster
FBpp0071811 Q9W1Y2 Drosophila melanogaster
FBpp0288534 Q9W1Y3 Drosophila melanogaster
FBpp0307779 Q9VN68 Drosophila melanogaster
FBpp0307778 Q2M1E6 Drosophila melanogaster
FBpp0293740 Q9VSL8 Drosophila melanogaster
Q0E8Y1_DROME Q0E8Y1 Drosophila melanogaster
Q960C2_DROME Q960C2 Drosophila melanogaster
Q8T0K5_DROME Q8T0K5 Drosophila melanogaster
Q94544_DROME Q94544 Drosophila melanogaster
F0JAJ0 Drosophila melanogaster
D3DMX5 Drosophila melanogaster
D0IQH8 Drosophila melanogaster