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Pathway : 82500 MAP kinase activation in TLR cascade

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

26 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0024846 CG7393 p38b p38b FlyBase D. melanogaster
FBgn0010303 CG4353 hep hemipterous FlyBase D. melanogaster
FBgn0015765 CG5475 Mpk2 Mpk2 FlyBase D. melanogaster
FBgn0003256 CG12559 rl rolled FlyBase D. melanogaster
FBgn0004106 CG5363 cdc2 cdc2 FlyBase D. melanogaster
FBgn0000229 CG5680 bsk basket FlyBase D. melanogaster
FBgn0024326 CG9738 Mkk4 MAP kinase kinase 4 FlyBase D. melanogaster
FBgn0001297 CG33956 kay kayak FlyBase D. melanogaster
FBgn0265464 CG10961 Traf6 TNF-receptor-associated factor 6 FlyBase D. melanogaster
FBgn0005638 CG4354 slbo slow border cells FlyBase D. melanogaster
FBgn0010269 CG15793 Dsor1 Downstream of raf1 FlyBase D. melanogaster
FBgn0010441 CG5974 pll pelle FlyBase D. melanogaster
FBgn0001291 CG2275 Jra Jun-related antigen FlyBase D. melanogaster
FBgn0004177 CG7109 mts microtubule star FlyBase D. melanogaster
FBgn0024222 CG4201 ird5 immune response deficient 5 FlyBase D. melanogaster
FBgn0042693 CG7913 PP2A-B' PP2A-B' FlyBase D. melanogaster
FBgn0020412 CG6297 JIL-1 JIL-1 FlyBase D. melanogaster
FBgn0086358 CG7417 Tab2 TAK1-associated binding protein 2 FlyBase D. melanogaster
FBgn0260439 CG17291 Pp2A-29B Protein phosphatase 2A at 29B FlyBase D. melanogaster
FBgn0036844 CG14080 Mkp3 Mitogen-activated protein kinase phosphatase 3 FlyBase D. melanogaster
FBgn0261524 CG12244 lic licorne FlyBase D. melanogaster
FBgn0026323 CG18492 Tak1 TGF-beta activated kinase 1 FlyBase D. melanogaster
FBgn0265784 CG6103 CrebB Cyclic-AMP response element binding protein B FlyBase D. melanogaster
FBgn0013987 CG3086 MAPk-Ak2 MAP kinase activated protein-kinase-2 FlyBase D. melanogaster
FBgn0041205 CG16910 key kenny FlyBase D. melanogaster
FBgn0262866 CG17596 S6kII Ribosomal protein S6 kinase II FlyBase D. melanogaster

45 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073578 Q23977 Drosophila melanogaster
FBpp0082977 Q9VEC6 Drosophila melanogaster
FBpp0082975 Q0KI58 Drosophila melanogaster
FBpp0082976 Q8IN90 Drosophila melanogaster
FBpp0082978 Q8IN89 Drosophila melanogaster
FBpp0085704 Q6NQZ7 Drosophila melanogaster
FBpp0099941 A8MPH9 Drosophila melanogaster
FBpp0099974 P36179 Drosophila melanogaster
FBpp0079148 P23696 Drosophila melanogaster
FBpp0070802 P49071 Drosophila melanogaster
FBpp0073551 O62602 Drosophila melanogaster
FBpp0079641 P23572 Drosophila melanogaster
FBpp0079676 P92208 Drosophila melanogaster
FBpp0081378 O61444 Drosophila melanogaster
FBpp0112426 P40417 Drosophila melanogaster
FBpp0077011 Q9V3Q6 Drosophila melanogaster
FBpp0077052 Q9VR61 Drosophila melanogaster
FBpp0072179 Q02637 Drosophila melanogaster
FBpp0074802 Q9VVW5 Drosophila melanogaster
FBpp0087499 P18289 Drosophila melanogaster
FBpp0083965 O62618 Drosophila melanogaster
FBpp0071248 Q24324 Drosophila melanogaster
FBpp0075965 Q9V3I5 Drosophila melanogaster
FBpp0084549 Q05652 Drosophila melanogaster
FBpp0080111 O61443 Drosophila melanogaster
FBpp0288515 P21525 Drosophila melanogaster
FBpp0074326 Q9VWW0 Drosophila melanogaster
FBpp0071136 Q9W3I9 Drosophila melanogaster
FBpp0288758 Q5BIJ2 Drosophila melanogaster
FBpp0288759 B7Z0L6 Drosophila melanogaster