Curated | false |
Description: | Authored: Jassal, B, 2005-06-16 12:47:23The target of rapamycin (TOR) proteins are large protein kinases, evolutionarily conserved from yeast to humans. Under optimal nutritional conditions, TOR propagates the insulin-like signal to downstream effectors of cell growth such as D4EBP and DS6K. When nutrients are deficient, TOR transmits no signal and insulin signaling is inhibited. |