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Pathway : 34799 Costimulation by the CD28 family

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

18 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0027492 CG5643 wdb widerborst FlyBase D. melanogaster
FBgn0003371 CG2621 sgg shaggy FlyBase D. melanogaster
FBgn0010341 CG12530 Cdc42 Cdc42 FlyBase D. melanogaster
FBgn0014011 CG8556 Rac2 Rac2 FlyBase D. melanogaster
FBgn0010333 CG2248 Rac1 Rac1 FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0005198 CG6975 gig gigas FlyBase D. melanogaster
FBgn0031006 CG8002 rictor rapamycin-insensitive companion of Tor FlyBase D. melanogaster
FBgn0033935 CG10105 Sin1 SAPK-interacting protein 1 FlyBase D. melanogaster
FBgn0028978 CG5408 trbl tribbles FlyBase D. melanogaster
FBgn0020386 CG1210 Pdk1 Phosphoinositide-dependent kinase 1 FlyBase D. melanogaster
FBgn0014001 CG10295 Pak PAK-kinase FlyBase D. melanogaster
FBgn0264691 CG3004 Lst8 FlyBase D. melanogaster
FBgn0021796 CG5092 Tor Target of rapamycin FlyBase D. melanogaster
FBgn0004177 CG7109 mts microtubule star FlyBase D. melanogaster
FBgn0024222 CG4201 ird5 immune response deficient 5 FlyBase D. melanogaster
FBgn0042693 CG7913 PP2A-B' PP2A-B' FlyBase D. melanogaster
FBgn0260439 CG17291 Pp2A-29B Protein phosphatase 2A at 29B FlyBase D. melanogaster

37 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0072614 P40792 Drosophila melanogaster
FBpp0082977 Q9VEC6 Drosophila melanogaster
FBpp0082975 Q0KI58 Drosophila melanogaster
FBpp0082976 Q8IN90 Drosophila melanogaster
FBpp0082978 Q8IN89 Drosophila melanogaster
FBpp0080003 Q9VK45 Drosophila melanogaster
FBpp0074458 Q9VWJ6 Drosophila melanogaster
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0099974 P36179 Drosophila melanogaster
FBpp0301154 P40793 Drosophila melanogaster
FBpp0079148 P23696 Drosophila melanogaster
FBpp0305023 P48554 Drosophila melanogaster
FBpp0072366 Q9W0V1 Drosophila melanogaster
FBpp0070449 P18431 Drosophila melanogaster
FBpp0084573 Q9VB23 Drosophila melanogaster
FBpp0077893 Q9V3Z1 Drosophila melanogaster
FBpp0074588 Q9VW83 Drosophila melanogaster
FBpp0081211 Q9VI13 Drosophila melanogaster
FBpp0086616 Q9V719 Drosophila melanogaster
FBpp0071303 Q9W328 Drosophila melanogaster
FBpp0288758 Q5BIJ2 Drosophila melanogaster
FBpp0288759 B7Z0L6 Drosophila melanogaster
FBpp0288760 B7Z0L7 Drosophila melanogaster
IKKB_DROME Q9VEZ5 Drosophila melanogaster
Q7YU91_DROME Q7YU91 Drosophila melanogaster
B7Z0W0_DROME B7Z0W0 Drosophila melanogaster
Q24213_DROME Q24213 Drosophila melanogaster
Q9U9B0_DROME Q9U9B0 Drosophila melanogaster
Q24190_DROME Q24190 Drosophila melanogaster
D2NUL2_DROME D2NUL2 Drosophila melanogaster