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Pathway : 127468 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

8 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0011676 CG6713 Nos Nitric oxide synthase FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0003162 CG9441 Pu Punch FlyBase D. melanogaster
FBgn0003141 CG16784 pr purple FlyBase D. melanogaster
FBgn0030041 CG12116 CG12116 FlyBase D. melanogaster
FBgn0014032 CG12117 Sptr Sepiapterin reductase FlyBase D. melanogaster
FBgn0001233 CG1242 Hsp83 Heat shock protein 83 FlyBase D. melanogaster
FBgn0004087 CG14887 Dhfr Dihydrofolate reductase FlyBase D. melanogaster

14 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0079777 Q27571 Drosophila melanogaster
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0071507 P48596 Drosophila melanogaster
FBpp0088417 P48611 Drosophila melanogaster
FBpp0071184 O76752 Drosophila melanogaster
FBpp0072904 P02828 Drosophila melanogaster
FBpp0071183 Q9W3F1 Drosophila melanogaster
FBpp0082746 P17719 Drosophila melanogaster
B4F5K6_DROME B4F5K6 Drosophila melanogaster
C0MLI5_DROME C0MLI5 Drosophila melanogaster
C0MLI6_DROME C0MLI6 Drosophila melanogaster
B4F5L3_DROME B4F5L3 Drosophila melanogaster
C0MLI9_DROME C0MLI9 Drosophila melanogaster
B4F5L2_DROME B4F5L2 Drosophila melanogaster