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Pathway : 149442 Regulation of Cholesterol Biosynthesis by SREBP (SREBF)

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

30 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0261283 CG8522 HLH106 Helix loop helix protein 106 FlyBase D. melanogaster
FBgn0263782 CG10367 Hmgcr HMG Coenzyme A reductase FlyBase D. melanogaster
FBgn0033010 CG3136 Atf6 Atf6 FlyBase D. melanogaster
FBgn0039169 CG5669 Spps Sp1-like factor for pairing sensitive-silencing FlyBase D. melanogaster
FBgn0260960 CG3971 Baldspot Baldspot FlyBase D. melanogaster
FBgn0038876 CG5919 CG5919 FlyBase D. melanogaster
FBgn0033246 CG11198 ACC Acetyl-CoA carboxylase FlyBase D. melanogaster
FBgn0040001 CG17374 CG17374 FlyBase D. melanogaster
FBgn0020255 CG1404 Ran Ran FlyBase D. melanogaster
FBgn0025373 CG12389 Fpps Farnesyl pyrophosphate synthase FlyBase D. melanogaster
FBgn0262743 CG2637 Fs(2)Ket Female sterile (2) Ketel FlyBase D. melanogaster
FBgn0027571 CG3523 CG3523 FlyBase D. melanogaster
FBgn0038947 CG7073 Sar1 Sar1 ortholog (S. cerevisiae) FlyBase D. melanogaster
FBgn0042627 CG3524 v(2)k05816 v(2)k05816 FlyBase D. melanogaster
FBgn0061359 CG33671 CG33671 FlyBase D. melanogaster
FBgn0262125 CG1250 Sec23 Sec23 ortholog (S. cerevisiae) FlyBase D. melanogaster
FBgn0033052 CG33131 SCAP SREBP cleavage activating protein FlyBase D. melanogaster
FBgn0027579 CG5508 CG5508 FlyBase D. melanogaster
FBgn0010611 CG4311 Hmgs HMG Coenzyme A synthase FlyBase D. melanogaster
FBgn0033656 CG8988 S2P site-2 protease FlyBase D. melanogaster
FBgn0029905 CG3075 Nf-YC Nuclear factor Y-box C FlyBase D. melanogaster
FBgn0034657 CG17952 LBR Lamin B receptor FlyBase D. melanogaster
FBgn0019662 CG8593 qm quemao FlyBase D. melanogaster
FBgn0032811 CG10268 CG10268 FlyBase D. melanogaster
FBgn0035993 CG3891 Nf-YA Nuclear factor Y-box A FlyBase D. melanogaster
FBgn0032816 CG10447 Nf-YB Nuclear factor Y-box B FlyBase D. melanogaster
FBgn0262126 CG10882 gho ghost FlyBase D. melanogaster
FBgn0037105 CG7169 S1P S1P FlyBase D. melanogaster
FBgn0033460 CG1472 sec24 sec24 FlyBase D. melanogaster
FBgn0030683 CG8239 CG8239 FlyBase D. melanogaster

69 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0085417 Q8SX87 Drosophila melanogaster
FBpp0085415 Q7K2V1 Drosophila melanogaster
FBpp0083607 Q9VD29 Drosophila melanogaster
FBpp0071630 Q8MLV1 Drosophila melanogaster
FBpp0086997 Q7K2V9 Drosophila melanogaster
FBpp0080807 Q9VIT2 Drosophila melanogaster
FBpp0085363 A1Z6J2 Drosophila melanogaster
FBpp0073328 Q9VZ23 Drosophila melanogaster
FBpp0077342 Q9VQL6 Drosophila melanogaster
FBpp0078360 Q9VNF8 Drosophila melanogaster
FBpp0074642 Q9VW37 Drosophila melanogaster
FBpp0077487 Q9VQ94 Drosophila melanogaster
FBpp0086289 Q7K4Q9 Drosophila melanogaster
FBpp0087266 Q7KN61 Drosophila melanogaster
FBpp0076557 Q9VS54 Drosophila melanogaster
FBpp0077343 Q9VQL7 Drosophila melanogaster
FBpp0078120 Q9VP10 Drosophila melanogaster
FBpp0083842 P14773 Drosophila melanogaster
FBpp0075114 Q9VV87 Drosophila melanogaster
FBpp0084620 Q8IMM7 Drosophila melanogaster
FBpp0084618 Q9Y137 Drosophila melanogaster
FBpp0084619 Q8IMM8 Drosophila melanogaster
FBpp0073903 Q9VXQ3 Drosophila melanogaster
FBpp0087169 Q7JZ56 Drosophila melanogaster
FBpp0080922 O18388 Drosophila melanogaster
FBpp0083457 Q9VDC2 Drosophila melanogaster
FBpp0297101 Q7PLB8 Drosophila melanogaster
FBpp0087536 A1Z813 Drosophila melanogaster
FBpp0080827 Q8ST61 Drosophila melanogaster
FBpp0308269 Q7JV23 Drosophila melanogaster