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Author :

Name  Imai Y

25 Publications

First Author Title Year Journal Volume Pages PubMed ID
Kanao T The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila. 2012 PLoS One 7 e30958 22393355
Gehrke S Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression. 2010 Nature 466 637-41 20671708
Neely GG A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. 2010 Cell 141 142-53 20371351
Imai Y Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila. 2008 EMBO J 27 2432-43 18701920
Kanao T Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila. 2010 Hum Mol Genet 19 3747-58 20624856
Wang JW Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1. 2007 J Neurosci 27 574-81 17234589
Imai Y The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila. 2010 PLoS Genet 6 e1001229 21151955
Yang Y Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. 2003 Neuron 37 911-24 12670421
Venderova K Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. 2009 Hum Mol Genet 18 4390-404 19692353
Yang Y Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. 2005 Proc Natl Acad Sci U S A 102 13670-5 16155123
Yang Y Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. 2006 Proc Natl Acad Sci U S A 103 10793-8 16818890
Wu Z Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance. 2013 Genes Dev 27 157-62 23348839
Liu S Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. 2012 PLoS Genet 8 e1002537 22396657
Fujiki R GlcNAcylation of histone H2B facilitates its monoubiquitination. 2011 Nature 480 557-60 22121020
Saito T Interviral homologies of the 30K proteins of tobamoviruses. 1988 Virology 167 653-6 3201760
Shiraishi K Rep helicase suppresses short-homology-dependent illegitimate recombination in Escherichia coli. 2005 Genes Cells 10 1015-23 16236131
Imai Y Sequence analysis of the MAGE gene family encoding human tumor-rejection antigens. 1995 Gene 160 287-90 7642112
Imai Y The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. 1999 Nature 398 777-85 10235259
Suzuki Y A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. 2001 Mol Cell 8 613-21 11583623
Imai Y Purification and characterization of human papillomavirus type 16 E7 protein with preferential binding capacity to the underphosphorylated form of retinoblastoma gene product. 1991 J Virol 65 4966-72 1870208
Ni M Targeting androgen receptor in estrogen receptor-negative breast cancer. 2011 Cancer Cell 20 119-31 21741601
Morita M The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza. 2013 Cell 153 112-25 23477864
Ohsawa K Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure. 1996 J Neurochem 67 89-97 8667030
Yanaka N Insertional mutation of the murine kisimo locus caused a defect in spermatogenesis. 2000 J Biol Chem 275 14791-4 10747865
Lee S The synaptic function of LRRK2. 2012 Biochem Soc Trans 40 1047-51 22988863