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Author :

Name  Lee WJ

27 Publications

First Author Title Year Journal Volume Pages PubMed ID
Nam HJ Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila. 2012 EMBO J 31 1253-65 22227521
Lee KS JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span. 2009 J Biol Chem 284 29454-61 19720829
Ha EM Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut. 2009 Nat Immunol 10 949-57 19668222
Kambris Z Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. 2006 Curr Biol 16 808-13 16631589
Ha EM An antioxidant system required for host protection against gut infection in Drosophila. 2005 Dev Cell 8 125-32 15621536
Ha EM Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. 2009 Dev Cell 16 386-97 19289084
De Gregorio E An immune-responsive Serpin regulates the melanization cascade in Drosophila. 2002 Dev Cell 3 581-92 12408809
Lee KA Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila. 2013 Cell 153 797-811 23663779
Nam HJ Involvement of pro-phenoloxidase 3 in lamellocyte-mediated spontaneous melanization in Drosophila. 2008 Mol Cells 26 606-10 18852525
Jang IH A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. 2006 Dev Cell 10 45-55 16399077
Ha EM A direct role for dual oxidase in Drosophila gut immunity. 2005 Science 310 847-50 16272120
Ryu JH An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity. 2006 EMBO J 25 3693-701 16858400
Ryu JH Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila. 2008 Science 319 777-82 18218863
Ryu JH The homeobox gene Caudal regulates constitutive local expression of antimicrobial peptide genes in Drosophila epithelia. 2004 Mol Cell Biol 24 172-85 14673153
Shin SC Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling. 2011 Science 334 670-4 22053049
Leulier F The Drosophila immune system detects bacteria through specific peptidoglycan recognition. 2003 Nat Immunol 4 478-84 12692550
Kim YS Gram-negative bacteria-binding protein, a pattern recognition receptor for lipopolysaccharide and beta-1,3-glucan that mediates the signaling for the induction of innate immune genes in Drosophila melanogaster cells. 2000 J Biol Chem 275 32721-7 10827089
Lee WJ Inhibition of mitogen-activated protein kinase by a Drosophila dual-specific phosphatase. 2000 Biochem J 349 Pt 3 821-8 10903144
Kwon HB Drosophila extracellular signal-regulated kinase involves the insulin-mediated proliferation of Schneider cells. 2002 J Biol Chem 277 14853-8 11834735
Kim SH Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase. 2002 Biochem J 361 143-51 11742539
Kim YS Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells. 2000 J Biol Chem 275 2071-9 10636911
Han SJ Molecular cloning and characterization of a Drosophila p38 mitogen-activated protein kinase. 1998 J Biol Chem 273 369-74 9417090
Han SH The moleskin gene product is essential for Caudal-mediated constitutive antifungal Drosomycin gene expression in Drosophila epithelia. 2004 Insect Mol Biol 13 323-7 15157233
Chen X A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production. 2011 Chem Commun (Camb) 47 4373-5 21399827
Shim SM Role of S5b/PSMD5 in proteasome inhibition caused by TNF-α/NFκB in higher eukaryotes. 2012 Cell Rep 2 603-15 22921402
Park JW Clustering of peptidoglycan recognition protein-SA is required for sensing lysine-type peptidoglycan in insects. 2007 Proc Natl Acad Sci U S A 104 6602-7 17409189
Hua KT N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity. 2011 Cancer Cell 19 218-31 21295525