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Author :

Name  Ocorr K

22 Publications

First Author Title Year Journal Volume Pages PubMed ID
Birse RT High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. 2010 Cell Metab 12 533-44 21035763
Lee JH Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. 2010 Science 327 1223-8 20203043
Wessells R d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. 2009 Aging Cell 8 542-52 19594484
Venkatesh TV Cardiac enhancer activity of the homeobox gene tinman depends on CREB consensus binding sites in Drosophila. 2000 Genesis 26 55-66 10660673
Neely GG A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. 2010 Cell 141 142-53 20371351
Qian L Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. 2011 J Cell Biol 193 1181-96 21690310
Grossman TR Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. 2011 PLoS Genet 7 e1002344 22072978
Buechling T Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies. 2009 Dev Biol 328 483-92 19233157
Qian L Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease. 2008 Proc Natl Acad Sci U S A 105 19833-8 19074289
Ocorr K Age-related cardiac disease model of Drosophila. 2007 Mech Ageing Dev 128 112-6 17125816
Akasaka T The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. 2006 Proc Natl Acad Sci U S A 103 11999-2004 16882722
Lim HY Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. 2011 Genes Dev 25 189-200 21245170
Ocorr K KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. 2007 Proc Natl Acad Sci U S A 104 3943-8 17360457
Melkani GC The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. 2011 PLoS One 6 e22579 21799905
Taghli-Lamallem O Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. 2008 Aging Cell 7 237-49 18221418
Cammarato A Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. 2008 Mol Biol Cell 19 553-62 18045988
Eleftherianos I ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. 2011 Proc Natl Acad Sci U S A 108 12024-9 21719711
Alayari NN Fluorescent labeling of Drosophila heart structures. 2009 J Vis Exp     19826399
Shahrestani P Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner. 2009 PLoS One 4 e6867 19718456
Mery A The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. 2008 J Exp Biol 211 15-23 18083727
Harpaz N Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen. 2013 PLoS Genet 9 e1003597 23825967
Tang M Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling. 2013 Circ Cardiovasc Genet 6 472-80 24046329