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Author :

Name  Chen D

69 Publications

First Author Title Year Journal Volume Pages PubMed ID
Zhang Y Analyses of mental dysfunction-related ACSl4 in Drosophila reveal its requirement for Dpp/BMP production and visual wiring in the brain. 2009 Hum Mol Genet 18 3894-905 19617635
Zhao S The highly conserved LAMMER/CLK2 protein kinases prevent germ cell overproliferation in Drosophila. 2013 Dev Biol 376 163-70 23376537
Sathyanarayanan S Identification of novel genes involved in light-dependent CRY degradation through a genome-wide RNAi screen. 2008 Genes Dev 22 1522-33 18519643
Dietzl G A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. 2007 Nature 448 151-6 17625558
Tan H MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats. 2012 PLoS Genet 8 e1002681 22570635
Yang Y The bantam microRNA is associated with drosophila fragile X mental retardation protein and regulates the fate of germline stem cells. 2009 PLoS Genet 5 e1000444 19343200
Xia L The niche-dependent feedback loop generates a BMP activity gradient to determine the germline stem cell fate. 2012 Curr Biol 22 515-21 22365848
Mummery-Widmer JL Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. 2009 Nature 458 987-92 19363474
Yang L Argonaute 1 regulates the fate of germline stem cells in Drosophila. 2007 Development 134 4265-72 17993467
Chen D Dpp signaling silences bam transcription directly to establish asymmetric divisions of germline stem cells. 2003 Curr Biol 13 1786-91 14561403
Wang H Effective gene silencing in Drosophila ovarian germline by artificial microRNAs. 2011 Cell Res 21 700-3 21423277
Jiang X Otefin, a nuclear membrane protein, determines the fate of germline stem cells in Drosophila via interaction with Smad complexes. 2008 Dev Cell 14 494-506 18410727
Chen D Gene circuitry controlling a stem cell niche. 2005 Curr Biol 15 179-84 15668176
Xia L The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response. 2010 Cell 143 978-90 21145463
Chen D Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila. 2009 Development 136 4133-42 19906849
Hegde P Mutational analysis of the Shab-encoded delayed rectifier K(+) channels in Drosophila. 1999 J Biol Chem 274 22109-13 10419540
Nagao A Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis. 2010 RNA 16 2503-15 20980675
Liu Z Drosophila Acyl-CoA synthetase long-chain family member 4 regulates axonal transport of synaptic vesicles and is required for synaptic development and transmission. 2011 J Neurosci 31 2052-63 21307243
Wang GK Regulation of the cycling of timeless (tim) RNA. 2001 J Neurobiol 47 161-75 11333398
Wu MN SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker. 2010 Nat Neurosci 13 69-75 20010822
Chen D High-resolution, high-throughput SNP mapping in Drosophila melanogaster. 2008 Nat Methods 5 323-9 18327265
Zheng X An isoform-specific mutant reveals a role of PDP1 epsilon in the circadian oscillator. 2009 J Neurosci 29 10920-7 19726650
Luo W Old flies have a robust central oscillator but weaker behavioral rhythms that can be improved by genetic and environmental manipulations. 2012 Aging Cell 11 428-38 22268765
Liu Y C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. 2009 Science 325 750-3 19661431
Nishida KM Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. 2009 EMBO J 28 3820-31 19959991
Chen D A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell. 2003 Development 130 1159-70 12571107
Yang L Fragile X mental retardation protein modulates the fate of germline stem cells in Drosophila. 2007 Hum Mol Genet 16 1814-20 17519221
Schnorrer F Positional cloning by fast-track SNP-mapping in Drosophila melanogaster. 2008 Nat Protoc 3 1751-65 18948975
Olsen DS Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase. 1998 Genetics 149 1495-509 9649537
Chen D HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. 2009 PLoS Genet 5 e1000486 19461873