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Protein Domain : IPR000847

Name  Transcription regulator HTH, LysR Short Name  Tscrpt_reg_HTH_LysR
Type  Domain Description  Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family, groups together a range of proteins, including ampR, catM, catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR, metR, mkaC, mleR, nahR, nhaR, nodD, nolR, oxyR, pssR, rbcR, syrM, tcbR, tfdS and trpI [, , , , ]. The majority of these proteins appear to be transcription activatorsand most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini.

Publication Counts Displayer

1 Child Features

DB identifier Name Short Name Type
IPR003725 Molybdenum-binding protein, N-terminal ModE-bd_N Domain

0 Contains

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00126 PFAM IPR000847
PR00039 PRINTS IPR000847
PS50931 PROFILE IPR000847

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

6 Found In

DB identifier Name Short Name Type
IPR011781 D-serine deaminase transcriptional activator DsdC Family
IPR020890 Transcription regulator HTH, HdfR Tscrpt_reg_HTH_HdfR Family
IPR017685 Transcription regulator ArgP Tscrpt_reg_ArgP Family
IPR017786 Transcription factor, choline sulphate-utilisation, putative TF_choline_sulphate-util_put Family
IPR017724 Aminoethylphosphonate utilisation-associated transcription regulator, LysR-type Tscrpt_reg_LysR Family
IPR012787 Pca transcription factor PcaQ TF_PcaQ Family

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Transcription regulator HTH, LysR   GO:0003700 sequence-specific DNA binding transcription factor activity
Transcription regulator HTH, LysR   GO:0006355 regulation of transcription, DNA-templated

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Transcription regulator HTH, LysR   GO:0003700 sequence-specific DNA binding transcription factor activity
Transcription regulator HTH, LysR   GO:0006355 regulation of transcription, DNA-templated

1 Parent Features

DB identifier Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain

5 Proteins

DB identifier Primary Accession
Organism . Name
E3NVR8_CAERE E3NVR8 Caenorhabditis remanei
E3NVY8_CAERE E3NVY8 Caenorhabditis remanei
E3NWV8_CAERE E3NWV8 Caenorhabditis remanei
E3NUW9_CAERE E3NUW9 Caenorhabditis remanei
E3NWB2_CAERE E3NWB2 Caenorhabditis remanei