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Protein : IKKB_DROME D. melanogaster

Primary Accession  ? Q9VEZ5 Organism . Name  Drosophila melanogaster
MD5 Checksum  b12c97e776328c3fe3f9d4faad502622 UniProt Accession  Q9VEZ5
UniProt Name  IKKB_DROME Is UniProt Canonical  true
Is Fragment  false Length  751
Molecular Weight  86373 Name  Inhibitor of nuclear factor kappa-B kinase subunit beta

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Genomics

1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0024222 CG4201 ird5 immune response deficient 5 FlyBase D. melanogaster

Proteins

Protein --> Gene + chromosomal location and length of the gene.

Interactions

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Other

0 Components

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
Dm.1435 UniGene IKKB_DROME
NP_524751.3 RefSeq IKKB_DROME

2 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
Reactome data set  

1 Ec Numbers

Identifier Description
2.7.11.10  

0 Locations

74 Pathways

Identifier Name
105951 Immune System
103669 Adaptive Immune System
31031 TCR signaling
34799 Costimulation by the CD28 family
34686 Downstream TCR signaling
30546 CD28 co-stimulation
114684 CD28 dependent PI3K/Akt signaling
120473 Downstream Signaling Events Of B Cell Receptor (BCR)
120569 B Cell Activation
138322 Activation of NF-kappaB in B Cells
88681 Innate Immune System
34578 TRAF6 Mediated Induction of proinflammatory cytokines
113278 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
87442 activated TAK1 mediates p38 MAPK activation
139259 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
82500 MAP kinase activation in TLR cascade
168277 FCERI mediated NF-kB activation
112247 Cytokine Signaling in Immune system
167642 Role of LAT2/NTAL/LAB on calcium mobilization
149356 DAP12 interactions
166867 Fc epsilon receptor (FCERI) signaling
150048 DAP12 signaling
120387 RIP-mediated NFkB activation via ZBP1
120480 ZBP1(DAI) mediated induction of type I IFNs
120468 Cytosolic sensors of pathogen-associated DNA
131727 TRAF6 mediated NF-kB activation
139163 RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
112945 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
29229 NOD1/2 Signaling Pathway
91838 Toll Like Receptor TLR1:TLR2 Cascade

3 Protein Domains

DB identifier Name Short Name Type
IPR011009 Protein kinase-like domain Kinase-like_dom Domain
IPR000719 Protein kinase domain Prot_kinase_dom Domain
IPR008271 Serine/threonine-protein kinase, active site Ser/Thr_kinase_AS Active_site

0 Transcripts