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Protein Domain : IPR009398

Name  Adenylate cyclase-like Short Name  Adenylate_cyclase-like
Type  Family Description  Cyclic AMP (cAMP) is a ubiquitous signalling molecule which mediates many cellular processes by activating cAMP-dependent kinases and also inducing protein-protein interactions. This molecule is produced by the adenylate cyclase (AC) enzyme, using ATP as its substrate. Mammalian adenylate cyclase has nine closely related membrane-bound isoforms (AC1-9) showing significant sequence homology and sharing the same overall structure: two hydrophobic transmembrane domains, and two cytoplasmic domains that are responsible for the catalytic activity. These isoforms differ in both their tissue specificity and their regulation. Regulatory factors known to influence one or more of these isoforms include G proteins, protein kinases, calcium and calmodulin. For more information see [, ].This entry represents a region of unknown function found in many of these isoforms. It is part of the N-terminal cytoplasmic domain but its presence is not necessary for catalytic activity [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF06327 PFAM IPR009398

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Adenylate cyclase-like   GO:0004016 adenylate cyclase activity
Adenylate cyclase-like   GO:0009190 cyclic nucleotide biosynthetic process
Adenylate cyclase-like   GO:0016021 integral component of membrane

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Adenylate cyclase-like   GO:0004016 adenylate cyclase activity
Adenylate cyclase-like   GO:0009190 cyclic nucleotide biosynthetic process
Adenylate cyclase-like   GO:0016021 integral component of membrane

0 Parent Features

27 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073809 P32870 Drosophila melanogaster
FBpp0305810 M9PHL3 Drosophila melanogaster
FBpp0309409 M9PJN1 Drosophila melanogaster
FBpp0305812 M9PEL4 Drosophila melanogaster
FBpp0305813 M9PH52 Drosophila melanogaster
FBpp0294032 M9NF51 Drosophila melanogaster
FBpp0290915 Q9VP76 Drosophila melanogaster
FBpp0303099 M9PG27 Drosophila melanogaster
FBpp0298356 Q9VV68 Drosophila melanogaster
FBpp0298357 A8JNU1 Drosophila melanogaster
FBpp0303100 M9PID8 Drosophila melanogaster
FBpp0305550 M9PD54 Drosophila melanogaster
FBpp0293953 M9NG95 Drosophila melanogaster
FBpp0288261 Q29F42 Drosophila pseudoobscura
FBpp0288182 B5DMQ5 Drosophila pseudoobscura
FBpp0286399 B5DRB7 Drosophila pseudoobscura
FBpp0163037 B4KVN3 Drosophila mojavensis
FBpp0164960 B4L4F3 Drosophila mojavensis
FBpp0226104 B4LEW0 Drosophila virilis
FBpp0227028 B4LI53 Drosophila virilis
FBpp0233021 B4M2Q0 Drosophila virilis
FBpp0261111 B4PW68 Drosophila yakuba
FBpp0267369 B4PE71 Drosophila yakuba
FBpp0267728 B4IUK6 Drosophila yakuba
H2VI41_CAEJA H2VI41 Caenorhabditis japonica
Q9Y1V0_DROME Q9Y1V0 Drosophila melanogaster
Q7KLG6_DROME Q7KLG6 Drosophila melanogaster