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Protein Domain : IPR005203

Name  Hemocyanin, C-terminal Short Name  Hemocyanin_C
Type  Domain Description  Crustacean and cheliceratan hemocyanins (oxygen-transport proteins)and insect hexamerins (storage proteins) are homologous gene products, although the latter do not bind oxygen [].Haemocyanins are found in the haemolymph of many invertebrates. They are divided into 2 main groups, arthropodan and molluscan. These have structurally similar oxygen-binding centres, which are similar to the oxygen-binding centre of tyrosinases [], but their quaternary structures are arranged differently. The arthropodan proteins exist as hexamers comprising 3 heterogeneous subunits (a, b and c) and possess 1 oxygen-binding centre per subunit; and the molluscan proteins exist as cylindrical oligomers of 10 to 20 subunits and possess 7 or 8 oxygen-binding centres per subunit []. Although the proteins have similar amino acid compositions, the only real similarity in their primary sequences is in the region corresponding to the second copper-binding domain, which also shows similarity to the copper-binding domain of tyrosinases []. Hexamerins are proteins from the hemolymph of insects, which may serve as a store of amino acids for synthesis of adult proteins. They do not possess the copper-binding histidines present in hemocyanins []. This entry represents the C-terminal domain of hemocyanin and hexamerin proteins.

Publication Counts Displayer

0 Child Features

0 Contains

2 Cross References

Source . Name

Subject . Primary Identifier
PF03723 PFAM IPR005203

2 Data Sets

Name URL
TrEMBL data set
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

1 Parent Features

DB identifier Name Short Name Type
IPR014756 Immunoglobulin E-set Ig_E-set Domain

49 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0291497 Q7K2W6 Drosophila melanogaster
FBpp0088363 Q24388 Drosophila melanogaster
FBpp0073484 P11995 Drosophila melanogaster
FBpp0075491 Q04691 Drosophila melanogaster
FBpp0077690 P11996 Drosophila melanogaster
FBpp0072365 P11997 Drosophila melanogaster
FBpp0291496 Q9W1V6 Drosophila melanogaster
FBpp0087744 Q9V521 Drosophila melanogaster
FBpp0075521 Q9VUC9 Drosophila melanogaster
FBpp0308598 M9PFK6 Drosophila melanogaster
FBpp0301841 Q9VVP2 Drosophila melanogaster
FBpp0276704 Q290S1 Drosophila pseudoobscura
FBpp0274456 Q2M078 Drosophila pseudoobscura
FBpp0275110 Q2M079 Drosophila pseudoobscura
FBpp0275464 Q2LYZ7 Drosophila pseudoobscura
FBpp0275972 B5E0Y5 Drosophila pseudoobscura
FBpp0276429 Q28ZC9 Drosophila pseudoobscura
FBpp0283875 B5DYG0 Drosophila pseudoobscura
FBpp0285792 B5DK98 Drosophila pseudoobscura
FBpp0160756 B4KV66 Drosophila mojavensis
FBpp0162805 B4L048 Drosophila mojavensis
FBpp0162979 B4KV64 Drosophila mojavensis
FBpp0167276 B4KG09 Drosophila mojavensis
FBpp0168504 B4KNJ9 Drosophila mojavensis
FBpp0168644 B4KLP9 Drosophila mojavensis
FBpp0169864 B4KUA2 Drosophila mojavensis
FBpp0172291 B4KDA4 Drosophila mojavensis
FBpp0225975 B4LFZ7 Drosophila virilis
FBpp0228169 B4LFZ5 Drosophila virilis
FBpp0228342 B4LHX5 Drosophila virilis