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Protein Domain : IPR018552

Name  Centromere protein X Short Name  CENP-X
Type  Family Description  Centromere protein X (CENP-X) is a component of several different complexes, including the multisubunit FA complex, the heterotetrameric CENP-T-W-S-X complex and the APITD1/CENPS complex. The Fanconi anemia (FA) core complex involved in DNA damage repair and genome maintenance. The FA complex is composed of CENPS, FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9, FANCM, FAAP24 and CENPX. Interacts with CENPS, FANCM and FAAP24 [, ].The CENP-T-W-S-X complex binds, supercoils DNA and plays an important role in kinetochore assembly [].The APITD1/CENPS complex is composed of at least of CENP-S and CENP-X and is essential for the stable assembly of the outer kinetchore [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF09415 PFAM IPR018552

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Centromere protein X   GO:0006281 DNA repair
Centromere protein X   GO:0051382 kinetochore assembly

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Centromere protein X   GO:0006281 DNA repair
Centromere protein X   GO:0051382 kinetochore assembly

0 Parent Features

4 Proteins

DB identifier Primary Accession
Organism . Name
A8WRA8_CAEBR A8WRA8 Caenorhabditis briggsae
G0P5M1_CAEBE G0P5M1 Caenorhabditis brenneri
Q20071_CAEEL Q20071 Caenorhabditis elegans
E3M6S7_CAERE E3M6S7 Caenorhabditis remanei