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Protein Domain : IPR000754

Name  Ribosomal protein S9 Short Name  Ribosomal_S9
Type  Family Description  Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms.The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites [, ]. About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to - the small (S1 to S31) and the large (L1 to L44). Usually they decorate the rRNA cores of the subunits. Many ribosomal proteins, particularly those of the large subunit, are composed of a globular, surfaced-exposed domain with long finger-like projections that extend into the rRNA core to stabilise its structure. Most of the proteins interact with multiple RNA elements, often from different domains. In the large subunit, about 1/3 of the 23S rRNA nucleotides are at least in van der Waal's contact with protein, and L22 interacts with all six domains of the 23S rRNA. Proteins S4 and S7, which initiate assembly of the 16S rRNA, are located at junctions of five and four RNA helices, respectively. In this way proteins serve to organise and stabilise the rRNA tertiary structure. While the crucial activities of decoding and peptide transfer are RNA based, proteins play an active role in functions that may have evolved to streamline the process of protein synthesis. In addition to their function in the ribosome, many ribosomal proteins have some function 'outside' the ribosome [, ].Ribosomal protein S9 is one of the proteins from the small ribosomal subunit. It belongs to the S9P family of ribosomal proteins which, on the basis of sequence similarities [, ],groups bacterial; algal chloroplast; cyanelle and archaeal S9 proteins; and mammalian; plant; and yeast mitochondrial ribosomal S9 proteins. These proteins adopt a beta-alpha-beta fold similar to that found in numerous RNA/DNA-binding proteins, as well as in kinases from the GHMP kinase family [].

Publication Counts Displayer

2 Child Features

DB identifier Name Short Name Type
IPR019958 Ribosomal protein S9, archaeal Ribosomal_S9_archaeal Family
IPR023035 Ribosomal protein S9, bacterial/plastid Ribosomal_S9_bac/plastid Family

1 Contains

DB identifier Name Short Name Type
IPR020574 Ribosomal protein S9, conserved site Ribosomal_S9_CS Conserved_site

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PTHR21569 PANTHER IPR000754
PF00380 PFAM IPR000754

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ribosomal protein S9   GO:0003735 structural constituent of ribosome
Ribosomal protein S9   GO:0006412 translation
Ribosomal protein S9   GO:0005840 ribosome

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ribosomal protein S9   GO:0003735 structural constituent of ribosome
Ribosomal protein S9   GO:0006412 translation
Ribosomal protein S9   GO:0005840 ribosome

0 Parent Features

21 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0071766 Q9W237 Drosophila melanogaster
FBpp0081263 Q8SXF0 Drosophila melanogaster
FBpp0277797 Q290H8 Drosophila pseudoobscura
FBpp0281172 Q294L5 Drosophila pseudoobscura
FBpp0170233 B4KQI0 Drosophila mojavensis
FBpp0172056 B4K7I7 Drosophila mojavensis
FBpp0239115 B4M0V0 Drosophila virilis
FBpp0256117 B4IUW4 Drosophila yakuba
FBpp0270774 B4PRD6 Drosophila yakuba
A8XDK5_CAEBR A8XDK5 Caenorhabditis briggsae
A8XP84_CAEBR A8XP84 Caenorhabditis briggsae
B4LPS9_DROVI B4LPS9 Drosophila virilis
H2VLE0_CAEJA H2VLE0 Caenorhabditis japonica
K7I0H4_CAEJA K7I0H4 Caenorhabditis japonica
H2W673_CAEJA H2W673 Caenorhabditis japonica
B3VAB9_CAEBE B3VAB9 Caenorhabditis brenneri
G0N5I0_CAEBE G0N5I0 Caenorhabditis brenneri
RS16_CAEEL Q22054 Caenorhabditis elegans
RT09_CAEEL P34388 Caenorhabditis elegans
E3LT05_CAERE E3LT05 Caenorhabditis remanei
E3NCK4_CAERE E3NCK4 Caenorhabditis remanei