modENCODE |  Help |  blog

Protein Domain : IPR029175

Name  Exocyst complex component Sec5 Short Name  Sec5
Type  Family Description  This entry represents the yeast Sec5 protein and its homologues from plants and animals. In S. cerevisiae, Sec5 is an essential component of the exocyst complex, which is composed of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84 []. The exocyst complex tethers post-Golgi secretory vesicles to the plasma membrane before soluble NSF attachment protein receptor (SNARE)-mediated membrane fusion [].In mammals, active form (GTP-bound) of Ral GTPase interacts with Sec5 and Exo84 and regulates the assembly interface of a full octameric exocyst complex []. Similar to yeast exocyst, the mammalian exocyst has been directly linked to post-Golgi targeting of secretory vesicles to discreet membrane sites [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF15469 PFAM IPR029175

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Exocyst complex component Sec5   GO:0006893 Golgi to plasma membrane transport
Exocyst complex component Sec5   GO:0000145 exocyst

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Exocyst complex component Sec5   GO:0006893 Golgi to plasma membrane transport
Exocyst complex component Sec5   GO:0000145 exocyst

0 Parent Features

11 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0077208 Q9VQQ9 Drosophila melanogaster
FBpp0280361 Q29N69 Drosophila pseudoobscura
FBpp0166370 B4KJL7 Drosophila mojavensis
FBpp0232074 B4LSG5 Drosophila virilis
FBpp0263245 B4NXW8 Drosophila yakuba
A8WPA7_CAEBR A8WPA7 Caenorhabditis briggsae
H2WD73_CAEJA H2WD73 Caenorhabditis japonica
G0PDQ2_CAEBE G0PDQ2 Caenorhabditis brenneri
G0NEC6_CAEBE G0NEC6 Caenorhabditis brenneri
EXOC2_CAEEL Q22706 Caenorhabditis elegans
E3N3A9_CAERE E3N3A9 Caenorhabditis remanei