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Protein Domain : IPR026739

Name  AP complex subunit beta Short Name  AP_beta
Type  Family Description  Adaptor protein (AP) complexes function in protein transport via transport vesicles in different membrane traffic pathways. AP complexes are involved in the formation of clathrin-coated vesicles (CCVs) by recruiting the scaffold protein, clathrin. AP complexes are also involved in the cargo selection by recognising the sorting signals in proteins. Several AP complexes have been identified: AP-2 mediates endocytosis from the plasma membrane, while AP-1, AP-3 and AP-4 play a role in the endosomal/lysosomal sorting pathways [, ]. AP complexes are heterotetramers which consist of two large subunits, one medium subunit and one small subunit. One of the large subunits (alpha, gamma, delta and epsilon) mediates binding to the target membrane. The other large subunit (beta) recruits clathrin through the clathrin-binding sequence []. This entry represents the AP complexes beta subunit.

Publication Counts Displayer

2 Child Features

DB identifier Name Short Name Type
IPR026740 AP-3 complex subunit beta AP3_beta Family
IPR016342 AP-1, 2,4 complex subunit beta AP_complex_bsu_1_2_4 Family

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PTHR11134 PANTHER IPR026739

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
AP complex subunit beta   GO:0016192 vesicle-mediated transport

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
AP complex subunit beta   GO:0016192 vesicle-mediated transport

0 Parent Features

30 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0074558 Q24253 Drosophila melanogaster
FBpp0070670 Q9W4K1 Drosophila melanogaster
FBpp0272566 Q29H04 Drosophila pseudoobscura
FBpp0273370 Q29J51 Drosophila pseudoobscura
FBpp0165315 B4L6V2 Drosophila mojavensis
FBpp0170686 B4L5S4 Drosophila mojavensis
FBpp0230163 B4MA28 Drosophila virilis
FBpp0230906 B4M7B3 Drosophila virilis
FBpp0260880 B4PZ07 Drosophila yakuba
FBpp0261863 B4Q053 Drosophila yakuba
A8WJ62_CAEBR A8WJ62 Caenorhabditis briggsae
A8X9Q7_CAEBR A8X9Q7 Caenorhabditis briggsae
H2VWR5_CAEJA H2VWR5 Caenorhabditis japonica
K7IID6_CAEJA K7IID6 Caenorhabditis japonica
H2W356_CAEJA H2W356 Caenorhabditis japonica
K7HY71_CAEJA K7HY71 Caenorhabditis japonica
G0P737_CAEBE G0P737 Caenorhabditis brenneri
G0MFE7_CAEBE G0MFE7 Caenorhabditis brenneri
G0MKM1_CAEBE G0MKM1 Caenorhabditis brenneri
Q7YZG8_CAEEL Q7YZG8 Caenorhabditis elegans
Q9N4F3_CAEEL Q9N4F3 Caenorhabditis elegans
O62348_CAEEL O62348 Caenorhabditis elegans
O45718_CAEEL O45718 Caenorhabditis elegans
Q7YZG9_CAEEL Q7YZG9 Caenorhabditis elegans
O77290_DROME O77290 Drosophila melanogaster
Q7YU20_DROME Q7YU20 Drosophila melanogaster
Q960F2_DROME Q960F2 Drosophila melanogaster
E3N7P8_CAERE E3N7P8 Caenorhabditis remanei
E3LRV4_CAERE E3LRV4 Caenorhabditis remanei
E3LRV2_CAERE E3LRV2 Caenorhabditis remanei