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Protein Domain : IPR012295

Name  Beta2-adaptin/TBP, C-terminal domain Short Name  Beta2_adaptin/TBP_C_dom
Type  Domain Description  The TATA-box binding protein (TBP) is required forthe initiation of transcription by RNA polymerases I, II and III, from promoters with or without a TATA box [, ]. The C-terminal core of TBP (~180 residues) is highly conserved and contains two 77-amino acid repeats that produce a saddle-shaped structure that straddles the DNA; this region binds to the TATA box, and interacts with transcription factors and regulatory proteins []. The C-terminal of TBP shares structural similarity with the C-terminal of beta(2)-adaptin, which is one of four subunits that comprise the clathrin adaptor.

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0 Child Features

0 Contains

1 Cross References

Source . Name

Subject . Primary Identifier
G3DSA:3.30.310.10 GENE3D IPR012295

2 Data Sets

Name URL
TrEMBL data set
InterPro data set  

2 Found In

DB identifier Name Short Name Type
IPR000814 TATA-box binding protein TBP Family
IPR015445 TATA-Box binding protein-like TBP-like Family

0 GO Annotation

0 Ontology Annotations

0 Parent Features

61 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0074558 Q24253 Drosophila melanogaster
FBpp0071596 P20227 Drosophila melanogaster
FBpp0077384 Q9VQE6 Drosophila melanogaster
FBpp0079164 Q27896 Drosophila melanogaster
FBpp0305892 M9PHD8 Drosophila melanogaster
FBpp0289804 Q07DP5 Drosophila melanogaster
FBpp0290208 Q9VQE8 Drosophila melanogaster
FBpp0303139 Q8T052 Drosophila melanogaster
FBpp0277453 Q292B8 Drosophila pseudoobscura
FBpp0272566 Q29H04 Drosophila pseudoobscura
FBpp0287543 Q29KX5 Drosophila pseudoobscura
FBpp0272588 Q29I65 Drosophila pseudoobscura
FBpp0282506 B5DW52 Drosophila pseudoobscura
FBpp0287604 Q29L40 Drosophila pseudoobscura
FBpp0163548 B4L8M5 Drosophila mojavensis
FBpp0164691 B4KGV8 Drosophila mojavensis
FBpp0165315 B4L6V2 Drosophila mojavensis
FBpp0167088 B4KL50 Drosophila mojavensis
FBpp0167135 B4KEC3 Drosophila mojavensis
FBpp0168160 B4KTN6 Drosophila mojavensis
FBpp0172172 B4KL55 Drosophila mojavensis
FBpp0229334 B4MG38 Drosophila virilis
FBpp0230163 B4MA28 Drosophila virilis
FBpp0231702 B4LUC7 Drosophila virilis
FBpp0231788 B4LUT1 Drosophila virilis
FBpp0232107 B4LSL7 Drosophila virilis
FBpp0233802 B4M1W1 Drosophila virilis
FBpp0235734 B4LNQ7 Drosophila virilis
FBpp0237919 B4LUT6 Drosophila virilis
FBpp0258695 B4P8V0 Drosophila yakuba