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Protein Domain : IPR005821

Name  Ion transport domain Short Name  Ion_trans_dom
Type  Domain Description  This domain is found in sodium, potassium, and calcium ion channels proteins. The proteins have 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some Na channel proteins the domain is repeated four times, whereas in others (e.g. K channels) the protein forms a tetramer in the membrane. A bacterial structure of the protein is known for the last two helices but is not included in the Pfam family due to it lacking the first four helices.

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00520 PFAM IPR005821

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

40 Found In

DB identifier Name Short Name Type
IPR003949 Potassium channel, voltage-dependent, EAG K_chnl_volt-dep_EAG Family
IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG K_chnl_volt-dep_EAG/ELK/ERG Family
IPR003091 Potassium channel K_chnl Family
IPR002077 Voltage-dependent calcium channel, alpha-1 subunit VDCCAlpha1 Family
IPR004729 Transient receptor potential channel TRP_channel Family
IPR013333 Ryanodine receptor Ryan_recept Family
IPR015925 Ryanodine receptor-related Ryanodine_recept-rel Family
IPR003968 Potassium channel, voltage dependent, Kv K_chnl_volt-dep_Kv Family
IPR003937 Potassium channel, voltage dependent, KCNQ K_chnl_volt-dep_KCNQ Family
IPR003967 Potassium channel, voltage-dependent, ERG K_chnl_volt-dep_ERG Family
IPR003974 Potassium channel, voltage dependent, Kv3 K_chnl_volt-dep_Kv3 Family
IPR000493 Inositol 1,4,5-trisphosphate-binding protein receptor InsP3_rcpt-bd Family
IPR003975 Potassium channel, voltage dependent, Kv4 K_chnl_volt-dep_Kv4 Family
IPR003972 Potassium channel, voltage dependent, Kv1 K_chnl_volt-dep_Kv1 Family
IPR001696 Voltage gated sodium channel, alpha subunit Na_channel_asu Family
IPR003950 Potassium channel, voltage-dependent, ELK K_chnl_volt-dep_ELK Family
IPR015572 Voltage-dependent potassium channel protein Shaw, invertebrate Shaw_inv Family
IPR004048 Potassium channel, voltage dependent, Kv1.1 K_chnl_volt-dep_Kv1.1 Family
IPR003973 Potassium channel, voltage dependent, Kv2 K_chnl_volt-dep_Kv2 Family
IPR003947 Potassium channel, voltage dependent, KCNQ2 K_chnl_volt-dep_KCNQ2 Family
IPR015573 Potassium channel, voltage dependent, KCNQ4 KCQN4 Family
IPR004050 Potassium channel, voltage dependent, Kv1.3 K_chnl_volt-dep_Kv1.3 Family
IPR005404 Potassium channel, voltage dependent, Kv3.3 K_chnl_volt-dep_Kv3.3 Family
IPR004055 Potassium channel, voltage dependent, Kv4.2 K_chnl_volt-dep_Kv4.2 Family
IPR004053 Potassium channel, voltage dependent, Kv1.6 K_chnl_volt-dep_Kv1.6 Family
IPR004052 Potassium channel, voltage dependent, Kv1.5 K_chnl_volt-dep_Kv1.5 Family
IPR004049 Potassium channel, voltage dependent, Kv1.2 K_chnl_volt-dep_Kv1.2 Family
IPR008348 Transient receptor potential channel, vanilloid 4 TRPV4_channel Family
IPR005460 Transient receptor potential channel, canonical 4 TRPC4_channel Family
IPR005827 Potassium channel, voltage dependent, KCNQ1 K_chnl_volt-dep_KCQN1 Family

4 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ion transport domain   GO:0005216 ion channel activity
Ion transport domain   GO:0006811 ion transport
Ion transport domain   GO:0055085 transmembrane transport
Ion transport domain   GO:0016020 membrane

4 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ion transport domain   GO:0005216 ion channel activity
Ion transport domain   GO:0006811 ion transport
Ion transport domain   GO:0055085 transmembrane transport
Ion transport domain   GO:0016020 membrane

0 Parent Features

676 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0088415 Q9W433 Drosophila melanogaster
FBpp0111866 A8JUY8 Drosophila melanogaster
FBpp0293151 M9NGR9 Drosophila melanogaster
FBpp0293152 M9NDQ0 Drosophila melanogaster
FBpp0099778 Q56JH9 Drosophila melanogaster
FBpp0099780 A1Z9N7 Drosophila melanogaster
FBpp0072423 Q9W0T5 Drosophila melanogaster
FBpp0072078 Q7JPB9 Drosophila melanogaster
FBpp0087555 P48994 Drosophila melanogaster
FBpp0072323 Q9W0Y6 Drosophila melanogaster
FBpp0099777 A1Z9N8 Drosophila melanogaster
FBpp0081252 Q9VHY7 Drosophila melanogaster
FBpp0298324 M9NEE2 Drosophila melanogaster
FBpp0298325 M9NF25 Drosophila melanogaster
FBpp0298317 Q59E50 Drosophila melanogaster
FBpp0304665 M9PHD4 Drosophila melanogaster
FBpp0298323 P91645 Drosophila melanogaster
FBpp0298315 Q59E53 Drosophila melanogaster
FBpp0298316 Q59E52 Drosophila melanogaster
FBpp0298326 M9NGZ9 Drosophila melanogaster
FBpp0298314 Q59E51 Drosophila melanogaster
FBpp0089049 Q24270 Drosophila melanogaster
FBpp0087721 Q24498 Drosophila melanogaster
FBpp0078709 Q9VMR4 Drosophila melanogaster
FBpp0088509 Q9VUD5 Drosophila melanogaster
FBpp0308225 B7YZH3 Drosophila melanogaster
FBpp0308223 A8DYE2 Drosophila melanogaster
FBpp0071592 Q9W2D5 Drosophila melanogaster
FBpp0085981 A1ZB14 Drosophila melanogaster
FBpp0088332 Q8SYL2 Drosophila melanogaster