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Protein Domain : IPR000483

Name  Cysteine-rich flanking region, C-terminal Short Name  Cys-rich_flank_reg_C
Type  Domain Description  Leucine-rich repeats (LRR, see ) consist of 2-45 motifs of 20-30 amino acids in length that generally folds into an arc or horseshoe shape []. LRRs occur in proteins ranging from viruses to eukaryotes, and appear to provide a structural framework for the formation of protein-protein interactions []. Proteins containing LRRs include tyrosine kinase receptors, cell-adhesion molecules, virulence factors, and extracellular matrix-binding glycoproteins, and are involved in a variety of biological processes, including signal transduction, cell adhesion, DNA repair, recombination, transcription, RNA processing, disease resistance, apoptosis, and the immune response.LRRs are often flanked by cysteine-rich domains: an N-terminal LRR domain () and a C-terminal LRR domain. This entry represents the C-terminal LRR domain.

Publication Counts Displayer

0 Child Features

0 Contains

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF01463 PFAM IPR000483
SM00082 SMART IPR000483

2 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  

7 Found In

DB identifier Name Short Name Type
IPR020777 Tyrosine-protein kinase, neurotrophic receptor Tyr_kinase_NGF_rcpt Family
IPR020446 Tyrosine-protein kinase, neurotrophic receptor, type 3 Tyr_kin_neurotrophic_rcpt_3 Family
IPR020455 Tyrosine-protein kinase, neurotrophic receptor, type 2 Tyr_kin_neurotrophic_rcpt_2 Family
IPR020461 Tyrosine-protein kinase, neurotrophic receptor, type 1 Tyr_kinase_neurotrophic_rcpt_1 Family
IPR017241 Toll-like receptor Toll-like_receptor Family
IPR000434 Polycystic kidney disease type 1 protein PKD_1 Family
IPR006228 Polycystin cation channel Polycystin_cat Domain

0 GO Annotation

0 Ontology Annotations

0 Parent Features

210 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0079369 Q9VLE6 Drosophila melanogaster
FBpp0073218 Q9VZ84 Drosophila melanogaster
FBpp0073587 Q7KV24 Drosophila melanogaster
FBpp0085620 A1ZBR2 Drosophila melanogaster
FBpp0085182 Q9V9V6 Drosophila melanogaster
FBpp0301162 Q9VWI6 Drosophila melanogaster
FBpp0085638 Q7KIN0 Drosophila melanogaster
FBpp0084431 P08953 Drosophila melanogaster
FBpp0075624 Q9VU51 Drosophila melanogaster
FBpp0083079 Q9VE49 Drosophila melanogaster
FBpp0075570 Q9VU53 Drosophila melanogaster
FBpp0079836 Q9VKG1 Drosophila melanogaster
FBpp0077881 Q9VPF0 Drosophila melanogaster
FBpp0080311 Q9V430 Drosophila melanogaster
FBpp0084911 Q9VAD1 Drosophila melanogaster
FBpp0071763 Q9W266 Drosophila melanogaster
FBpp0073231 Q6AWM0 Drosophila melanogaster
FBpp0081991 Q9VGH2 Drosophila melanogaster
FBpp0071724 Q7JWP9 Drosophila melanogaster
FBpp0080064 Q9VK22 Drosophila melanogaster
FBpp0308988 A1Z9N6 Drosophila melanogaster
FBpp0303575 P24014 Drosophila melanogaster
FBpp0291490 A1ZBX8 Drosophila melanogaster
FBpp0309591 D0IQL1 Drosophila melanogaster
FBpp0305379 Q0KHN6 Drosophila melanogaster
FBpp0303108 M9PFH7 Drosophila melanogaster
FBpp0291294 A1ZAB1 Drosophila melanogaster
FBpp0293933 Q0E8F0 Drosophila melanogaster
FBpp0304518 Q9VK54 Drosophila melanogaster
FBpp0298807 Q297R4 Drosophila pseudoobscura