modENCODE |  Help |  blog

Protein Domain : IPR000210

Name  BTB/POZ-like Short Name  BTB/POZ-like
Type  Domain Description  The BTB (for BR-C, ttk and bab) []or POZ (for Pox virus and Zinc finger)[]domain is present near the N terminus of a fraction of zinc finger() proteins and in proteins that contain the motif such as Kelch and a family of pox virus proteins.The BTB/POZ domain mediates homomeric dimerisation and in some instancesheteromeric dimerisation [].The structure of the dimerised PLZF BTB/POZ domain has been solved andconsists of a tightly intertwined homodimer. The central scaffolding ofthe protein is made up of a cluster of alpha-helices flanked by shortbeta-sheets at both the top and bottom of the molecule [].POZ domains from several zinc finger proteins have been shown to mediatetranscriptional repression and to interact with components of histonedeacetylase co-repressor complexes including N-CoR and SMRT [, , ].The POZ or BTB domain is also known as BR-C/Ttk or ZiN.

Publication Counts Displayer

2 Child Features

DB identifier Name Short Name Type
IPR013069 BTB/POZ BTB_POZ Domain
IPR003131 Potassium channel tetramerisation-type BTB domain T1-type_BTB Domain

0 Contains

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PS50097 PROFILE IPR000210
SM00225 SMART IPR000210

3 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  
InterPro GO Annotation data set  

7 Found In

DB identifier Name Short Name Type
IPR003972 Potassium channel, voltage dependent, Kv1 K_chnl_volt-dep_Kv1 Family
IPR020467 Potassium channel, voltage dependent, Kv1.4 K_chnl_volt-dep_Kv1.4 Family
IPR004048 Potassium channel, voltage dependent, Kv1.1 K_chnl_volt-dep_Kv1.1 Family
IPR004350 Potassium channel, voltage dependent, Kv2.1 K_chnl_volt-dep_Kv2.1 Family
IPR004050 Potassium channel, voltage dependent, Kv1.3 K_chnl_volt-dep_Kv1.3 Family
IPR005404 Potassium channel, voltage dependent, Kv3.3 K_chnl_volt-dep_Kv3.3 Family
IPR004049 Potassium channel, voltage dependent, Kv1.2 K_chnl_volt-dep_Kv1.2 Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
BTB/POZ-like   GO:0005515 protein binding

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
BTB/POZ-like   GO:0005515 protein binding

1 Parent Features

DB identifier Name Short Name Type
IPR011333 BTB/POZ fold BTB/POZ_fold Domain

1310 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0071426 Q9W2S3 Drosophila melanogaster
FBpp0305260 M9PFM7 Drosophila melanogaster
FBpp0099866 A4V1Y7 Drosophila melanogaster
FBpp0089417 A4V1Y6 Drosophila melanogaster
FBpp0305259 Q2PDY1 Drosophila melanogaster
FBpp0099867 Q2PDY2 Drosophila melanogaster
FBpp0072382 Q0E8K5 Drosophila melanogaster
FBpp0307379 H1UUK0 Drosophila melanogaster
FBpp0307384 Q9VY72 Drosophila melanogaster
FBpp0307381 M9NEG1 Drosophila melanogaster
FBpp0307382 M9PJM9 Drosophila melanogaster
FBpp0085430 Q7JZ62 Drosophila melanogaster
FBpp0305171 Q7K187 Drosophila melanogaster
FBpp0070791 Q7YZ93 Drosophila melanogaster
FBpp0070790 Q9W458 Drosophila melanogaster
FBpp0075887 Q9VTJ5 Drosophila melanogaster
FBpp0305467 M9PDT5 Drosophila melanogaster
FBpp0305466 M9PE50 Drosophila melanogaster
FBpp0072538 Q9W0K7 Drosophila melanogaster
FBpp0305468 M9PGP8 Drosophila melanogaster
FBpp0300865 D5SHR0 Drosophila melanogaster
FBpp0071609 Q9W2F9 Drosophila melanogaster
FBpp0073518 Q9VYJ8 Drosophila melanogaster
FBpp0288661 B9A0N7 Drosophila melanogaster
FBpp0077004 Q9VRA7 Drosophila melanogaster
FBpp0073935 Q9VXL5 Drosophila melanogaster
FBpp0083063 Q8IN81 Drosophila melanogaster
FBpp0070252 M9MSM6 Drosophila melanogaster
FBpp0070251 Q24206 Drosophila melanogaster
FBpp0070256 D8FT05 Drosophila melanogaster