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Gene : Cpsf73 D. melanogaster

DB identifier  ? FBgn0261065 Secondary Identifier  ? CG7698
Name  ? Cleavage and polyadenylation specificity factor 73 Source  FlyBase
  • synonyms:
  • FBan0007698,
  • cleavage and polyadenylation specificity factor, 73kD-subunit,
  • dCPSF-73,
  • CPSF-73,
  • CG7698,
  • FBgn0038636,
  • CPSF73,
  • FBgn0261065,
  • FBgn0066368

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2 Alleles

DB identifier Symbol Allele Class Organism
FBal0205565 Cpsf73[GD3050]   Drosophila melanogaster
FBal0230749 Cpsf73[KK100438]   Drosophila melanogaster

17 Clones

Secondary Identifier DB identifier
EK133546 FBcl0058444
EK200645 FBcl0058570
EK237602 FBcl0058602
EK150124 FBcl0058670
EP00825 FBcl0090019
GM03308 FBcl0143721
RE63976 FBcl0212741
RE31408 FBcl0212751
Dmel_neb_012947_0357_3342 FBcl0369702
FGH126C04 FBcl0388478
CK01.145B.H2 FBcl0465605
33817 FBcl0465600
18862 FBcl0465531
273268 FBcl0465581
72009 FBcl0465568
214347.54 FBcl0465584
37778 FBcl0465591

5 Exons

DB identifier Symbol
FBgn0261065:5 Cpsf73:5
FBgn0261065:4 Cpsf73:4
FBgn0261065:3 Cpsf73:3
FBgn0261065:2 Cpsf73:2
FBgn0261065:1 Cpsf73:1

1 Transcripts

DB identifier Gene
FBtr0083690 Cpsf73

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083690-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083690-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42240 NCBI Entrez Gene identifiers FBgn0261065
67248 BioGRID FBgn0261065

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

4 Introns

DB identifier
Organism . Name
intron_FBgn0261065:5_FBgn0261065:4 Drosophila melanogaster
intron_FBgn0261065:4_FBgn0261065:3 Drosophila melanogaster
intron_FBgn0261065:3_FBgn0261065:2 Drosophila melanogaster
intron_FBgn0261065:2_FBgn0261065:1 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Cpsf73 none 0.137939611   19067489
Lipid storage Cpsf73 none 2.488703685   19067489
Histone pre-mRNA processing Cpsf73 Histone pre-mRNA processing defect 3   18042462
Alternative splicing Cpsf73 none sp   15492211
Constitutive protein secretion and Golgi organization (1) Cpsf73 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Cpsf73 none sp   16496002
Mutant human huntingtin aggregation Cpsf73 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Cpsf73 Flightless np   20220848
Muscle morphogenesis and function (1) Cpsf73 none np   20220848
Muscle morphogenesis and function (4) Cpsf73 none np   20220848
Heat nociception (1) Cpsf73 none -0.47   21074052
Heat nociception (1) Cpsf73 none -1.17   21074052
Heart development and function (1) Cpsf73 none 1   20371351
Serratia marcescens infection (1) Cpsf73 none -1   19520911
Notch pathway regulation (4) Cpsf73 Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Cpsf73 Completely lethal (pupal) sp   19363474
Notch induced transcription Cpsf73 none 0.29562 without Notch stimulation 20959007
Notch induced transcription Cpsf73 Upregulation of Notch pathway after Notch stimulation 2.3474 N(delta)ecn Notch stimulation 20959007
Notch induced transcription Cpsf73 none 0.72521 N(delta)ecn Notch stimulation 20959007
Self-renewal and differentiation in neural stem cells Cpsf73 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Self-renewal and differentiation in neural stem cells Cpsf73 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) Cpsf73 none -0.619   20074523
RTK-Ras-ERK pathway regulation (1) Cpsf73 Increased ERK phosphorylation after EGF stimulation 1.52 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Cpsf73 none -0.41 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cpsf73 none -0.68 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Cpsf73 none -0.42 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Cpsf73 none -0.45   23263283
Glycosylation regulation (1) Cpsf73 none sp   21203496

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