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Gene : nec D. melanogaster

DB identifier  ? FBgn0002930 Secondary Identifier  ? CG1857
Name  ? necrotic Source  FlyBase
  • synonyms:
  • Spn43Ac,
  • FBgn0002930,
  • Necrotic,
  • CG1857,
  • NEC,
  • anon-WO0118057.3,
  • necrotic serpin,
  • FBgn0024292,
  • SER3,
  • FBgn0033148,
  • Serine protease inhibitor 3,
  • FBan0001857,
  • serpin43Ac,
  • FBgn0063807,
  • FBgn0028676

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38 Alleles

DB identifier Symbol Allele Class Organism
FBal0120439 nec[+t7.0]   Drosophila melanogaster
FBal0039685 nec[18]   Drosophila melanogaster
FBal0035266 nec[9] amorphic allele - genetic evidence Drosophila melanogaster
FBal0146990 nec[16]   Drosophila melanogaster
FBal0035263 nec[6] amorphic allele - genetic evidence Drosophila melanogaster
FBal0101254 nec[unspecified]   Drosophila melanogaster
FBal0035261 nec[4] amorphic allele - genetic evidence Drosophila melanogaster
FBal0035264 nec[7] amorphic allele - genetic evidence Drosophila melanogaster
FBal0190454 nec[dsRNA.57-1473]   Drosophila melanogaster
FBal0039682 nec[15]   Drosophila melanogaster
FBal0146987 nec[22]   Drosophila melanogaster
FBal0035260 nec[2] amorphic allele - genetic evidence Drosophila melanogaster
FBal0146988 nec[20]   Drosophila melanogaster
FBal0035265 nec[8] amorphic allele - genetic evidence Drosophila melanogaster
FBal0035258 nec[12] amorphic allele - genetic evidence Drosophila melanogaster
FBal0035259 nec[13] amorphic allele - genetic evidence Drosophila melanogaster
FBal0039684 nec[17]   Drosophila melanogaster
FBal0035255 nec[1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0035257 nec[11] amorphic allele - genetic evidence Drosophila melanogaster
FBal0035256 nec[10] amorphic allele - genetic evidence Drosophila melanogaster
FBal0146989 nec[19]   Drosophila melanogaster
FBal0178679 nec[Npk]   Drosophila melanogaster
FBal0039686 nec[JR]   Drosophila melanogaster
FBal0197362 nec[K68Q.K70Q.K71Q.Scer\UAS]   Drosophila melanogaster
FBal0146986 nec[9.Scer\UAS]   Drosophila melanogaster
FBal0146991 nec[1.Scer\UAS]   Drosophila melanogaster
FBal0141025 nec[dsRNA.CopT.Scer\UAS]   Drosophila melanogaster
FBal0141024 nec[dsRNA.L.Scer\UAS]   Drosophila melanogaster
FBal0141023 nec[dsRNA.S.Scer\UAS]   Drosophila melanogaster
FBal0150320 nec[MtnA.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster

33 Clones

Secondary Identifier DB identifier
ESG0110c.E21_E09 FBcl0000664
AT26992 FBcl0017735
EC22258 FBcl0065103
EP05241 FBcl0078815
GH23919 FBcl0113647
GH21227 FBcl0113649
GH10112 FBcl0113651
GH01054 FBcl0113653
GH22817 FBcl0113657
GH26837 FBcl0113659
GH17608 FBcl0113669
GH18542 FBcl0113679
GH17392 FBcl0113681
GH07566 FBcl0113687
GH22377 FBcl0113691
GH26737 FBcl0113721
EK184358 FBcl0136712
EK265838 FBcl0136716
EK160259 FBcl0136724
EK228811 FBcl0136850
HL02838 FBcl0149311
HL07334 FBcl0149312
HL04407 FBcl0149313
LP16986 FBcl0183442
LP17213 FBcl0183443
EC054735 FBcl0301695
Dmel_dig_000401_0627_0323 FBcl0375934
101917 FBcl0444703
161390 FBcl0444847
214435.40 FBcl0444683

3 Exons

DB identifier Symbol
FBgn0002930:2 nec:2
FBgn0002930:1 nec:1
FBgn0002930:3 nec:3

1 Transcripts

DB identifier Gene
FBtr0089052 nec

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0089052-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089052-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
45908 NCBI Entrez Gene identifiers FBgn0002930
69974 BioGRID FBgn0002930

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 31.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 59.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 4.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 47.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 0.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 77.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 63.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 90.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 60.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 15.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 35.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 21.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 37.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 37.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 70.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 117.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 0.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 91.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 40.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 30.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 43.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 55.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 499.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 49.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 0.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 32.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 24.0
FBgn0002930 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 46.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0002930:3_FBgn0002930:2 Drosophila melanogaster
intron_FBgn0002930:2_FBgn0002930:1 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage nec none 0.118744654   19067489
Lipid storage nec none 0.710339604   19067489
Cell size and cell-cycle regulation (1) nec Decreased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (2) nec none 1.21   16496002
Cell size and cell-cycle regulation (3) nec none 420   16496002
Cell size and cell-cycle regulation (4) nec none below threshold   16496002
Heat nociception (1) nec Lethal 0.12   21074052
Heat nociception (1) nec Lethal -1.17   21074052
Heart development and function (1) nec none 1   20371351
Heart development and function (1) nec none 1   20371351
Serratia marcescens infection (1) nec none -2.78846153846153   19520911
Notch pathway regulation (4) nec Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) nec Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) nec Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation nec Increased P-JNK protein expression with PGN 2.61 60 min PGN induction 19893628
Blood cell homeostasis regulation (1) nec Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) nec Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) nec Increased melanotic mass formation 21.5   20540764
Blood cell homeostasis regulation (4) nec Increased melanotic mass formation 17.5   20540764
Blood cell homeostasis regulation (5) nec Lethal np   20540764
Blood cell homeostasis regulation (6) nec Increased melanotic mass formation 26.6   20540764
Blood cell homeostasis regulation (7) nec Increased melanotic mass formation 14.6   20540764
Blood cell homeostasis regulation (8) nec Lethal np   20540764
Hippo pathway regulation nec none 0.11   23263283
Glycosylation regulation (1) nec Lethal np   21203496

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