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Gene : Sik2 D. melanogaster

DB identifier  ? FBgn0025625 Secondary Identifier  ? CG4290
Name  ? Salt-inducible kinase 2 Source  FlyBase
  • synonyms:
  • SIK,
  • Salt-induced kinase 2,
  • FBgn0025625,
  • SIK2,
  • EG:22E5.8,
  • CG4290,
  • FBan0004290

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0265617 Sik2[Scer\UAS.cWa]   Drosophila melanogaster
FBal0231712 Sik2[KK102292]   Drosophila melanogaster
FBal0258122 Sik2[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0204219 Sik2[GD11275]   Drosophila melanogaster
FBal0258121 Sik2[Delta41]   Drosophila melanogaster
FBal0258123 Sik2[K170M.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0247848 Sik2[G366]   Drosophila melanogaster

15 Clones

Secondary Identifier DB identifier
EK069546 FBcl0070268
EK069538 FBcl0070668
EK206909 FBcl0071170
EK173029 FBcl0071208
GH06988 FBcl0127713
GH06888 FBcl0128159
RH42017 FBcl0265579
RH67885 FBcl0265739
SD11330 FBcl0278230
EC051028 FBcl0298410
EC055795 FBcl0298411
CK01.88B.B4 FBcl0454286
CK01.88B.D4 FBcl0454297
106689 FBcl0454293
147326 FBcl0454225

9 Exons

DB identifier Symbol
FBgn0025625:9 Sik2:9
FBgn0025625:8 Sik2:8
FBgn0025625:7 Sik2:7
FBgn0025625:6 Sik2:6
FBgn0025625:5 Sik2:5
FBgn0025625:4 Sik2:4
FBgn0025625:3 Sik2:3
FBgn0025625:2 Sik2:2
FBgn0025625:1 Sik2:1

1 Transcripts

DB identifier Gene
FBtr0070340 Sik2

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070340-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070340-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31170 NCBI Entrez Gene identifiers FBgn0025625
57714 BioGRID FBgn0025625

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 448.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 246.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 225.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 173.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 133.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 298.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 775.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 418.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 433.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 488.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 247.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 89.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 329.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 156.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 357.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 394.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 457.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 766.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 127.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 557.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 423.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 307.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 567.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 268.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1247.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 114.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 139.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 204.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 104.0
FBgn0025625 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 136.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0025625:9_FBgn0025625:8 Drosophila melanogaster
intron_FBgn0025625:8_FBgn0025625:7 Drosophila melanogaster
intron_FBgn0025625:7_FBgn0025625:6 Drosophila melanogaster
intron_FBgn0025625:6_FBgn0025625:5 Drosophila melanogaster
intron_FBgn0025625:5_FBgn0025625:4 Drosophila melanogaster
intron_FBgn0025625:4_FBgn0025625:3 Drosophila melanogaster
intron_FBgn0025625:3_FBgn0025625:2 Drosophila melanogaster
intron_FBgn0025625:2_FBgn0025625:1 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Sik2 none 0.573895966   19067489
Lipid storage Sik2 none 0.093395093   19067489
Cell cycle regulation (1) Sik2 none np   15616552
Cell cycle regulation (2) Sik2 none np   15616552
Cell size and cell-cycle regulation (1) Sik2 none sp   16496002
Muscle morphogenesis and function (1) Sik2 none np   20220848
Muscle morphogenesis and function (1) Sik2 none np   20220848
Heat nociception (1) Sik2 Developmentally lethal -0.95   21074052
Heat nociception (1) Sik2 none 0.56   21074052
Heart development and function (1) Sik2 none 1   20371351
Serratia marcescens infection (1) Sik2 none 0.494949494949494   19520911
Notch pathway regulation (4) Sik2 none 0   19363474
Notch pathway regulation (4) Sik2 none 0   19363474
Adiposity regulation (1) Sik2 none -0.387   20074523
Actin organization and cell morphology (1) Sik2 none np   19265526
Actin organization and cell morphology (2) Sik2 none np   19265526
Actin organization and cell morphology (3) Sik2 none np   19265526
Actin organization and cell morphology (4) Sik2 none np   19265526
Actin organization and cell morphology (5) Sik2 none np   19265526
Actin organization and cell morphology (6) Sik2 none np   19265526
Vaccinia virus infection Sik2 none sp   20585561
RTK-Ras-ERK pathway regulation (1) Sik2 none 0.04 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Sik2 none 0.21 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Sik2 none -0.22 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Sik2 Decreased ERK phosphorylation after sSpitz and EGF stimulation -1.84 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Sik2 none -2.63   23263283

0 Submissions