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Gene : S6kII D. melanogaster

DB identifier  ? FBgn0262866 Secondary Identifier  ? CG17596
Name  ? Ribosomal protein S6 kinase II Source  FlyBase
  • synonyms:
  • S6KII,
  • RSK,
  • dRSK,
  • rsk2,
  • FBgn0011285,
  • p90 ribosomal S6 kinase,
  • Ribosomal-S6-kinase,
  • FBgn0262866,
  • ign,
  • ignorant,
  • S6 kinase II,
  • CG17596,
  • RPS6-protein kinase-II,
  • FBgn0086241,
  • FBan0017596

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29 Alleles

DB identifier Symbol Allele Class Organism
FBal0268936 S6kII[K597M.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0268937 S6kII[T732A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0268938 S6kII[T732E.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0268939 S6kII[S515A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0268940 S6kII[S515D.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0262680 S6kII[GL00207]   Drosophila melanogaster
FBal0181737 S6kII[Scer\UAS.cBa]   Drosophila melanogaster
FBal0135821 S6kII[Scer\UAS.cRa]   Drosophila melanogaster
FBal0194031 S6kII[EP7363]   Drosophila melanogaster
FBal0194032 S6kII[D1] loss of function allele Drosophila melanogaster
FBal0194033 S6kII[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0194034 S6kII[K231R.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0194035 S6kII[K231R.K597R.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0194036 S6kII[K231M.K597M.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0194037 S6kII[R902A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0194038 S6kII[K213R.R902A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0246880 S6kII[G1845]   Drosophila melanogaster
FBal0208435 S6kII[GD1254]   Drosophila melanogaster
FBal0215315 S6kII[ign-P1]   Drosophila melanogaster
FBal0215316 S6kII[ign-Delta1P1]   Drosophila melanogaster
FBal0215319 S6kII[ign-Delta30-2]   Drosophila melanogaster
FBal0215317 S6kII[ign-Delta1P2]   Drosophila melanogaster
FBal0215318 S6kII[ign-Delta24-3]   Drosophila melanogaster
FBal0215321 S6kII[t6.5]   Drosophila melanogaster
FBal0215320 S6kII[ign-Delta58-1] loss of function allele Drosophila melanogaster
FBal0242393 S6kII[JF02814]   Drosophila melanogaster
FBal0220361 S6kII[T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0236132 S6kII[KK109199]   Drosophila melanogaster
FBal0272655 S6kII[NIG.17596R]   Drosophila melanogaster

33 Clones

Secondary Identifier DB identifier
AT18425 FBcl0029935
EP16435 FBcl0084011
EN04664 FBcl0097853
EK104427 FBcl0108078
EK271957 FBcl0108112
EK093342 FBcl0108126
EK147746 FBcl0108256
EK063263 FBcl0108292
EK113222 FBcl0108694
EK096243 FBcl0108928
EK061036 FBcl0108938
EK072752 FBcl0109654
GH08264 FBcl0110171
GH21818 FBcl0110179
RE35874 FBcl0202328
RE06367 FBcl0202525
SD05277 FBcl0286893
EC056288 FBcl0299248
EC055345 FBcl0299249
EC054882 FBcl0299250
EC053320 FBcl0299251
CK01.93A.E8 FBcl0462733
CK01.60A.H10 FBcl0462744
CK01.125C.C10 FBcl0462761
524062 FBcl0462800
CK01.122B.C4 FBcl0462916
CK01.170B.G5 FBcl0462976
166784 FBcl0462947
66677 FBcl0462773
36894 FBcl0462785

3 Exons

DB identifier Symbol
FBgn0262866:1 S6kII:1
FBgn0262866:2 S6kII:2
FBgn0262866:3 S6kII:3

2 Transcripts

DB identifier Gene
FBtr0333715 S6kII
FBtr0077360 S6kII

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0077360-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333715-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0077360-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333715-3-prime-utr Drosophila melanogaster

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98 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
33139 NCBI Entrez Gene identifiers FBgn0262866
59412 BioGRID FBgn0262866

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

2 Introns

DB identifier
Organism . Name
intron_FBgn0262866:1_FBgn0262866:3 Drosophila melanogaster
intron_FBgn0262866:1_FBgn0262866:2 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage S6kII none 0.957959155   19067489
Lipid storage S6kII none 0.881625511   19067489
ERK signaling S6kII ERK activation increased moderate   17086199
Cell cycle regulation (1) S6kII Increased G2/M DNA content sp   15616552
Cell cycle regulation (2) S6kII Increased G2/M DNA content np   15616552
Cell size and cell-cycle regulation (1) S6kII none sp   16496002
Cell size and cell-cycle regulation (1) S6kII none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) S6kII none sp   19543366
Muscle morphogenesis and function (1) S6kII none np   20220848
Heat nociception (1) S6kII none 0.55   21074052
Heart development and function (1) S6kII none 1   20371351
Serratia marcescens infection (1) S6kII none 0.379310344827586   19520911
Notch pathway regulation (4) S6kII Gain of bristles, planar polarity defects, notum malformation migration sp   19363474
Adiposity regulation (1) S6kII Decreased triglyceride expression -0.376   20074523
Adiposity regulation (2) S6kII none 0.227   20074523
Adiposity regulation (3) S6kII none 0.119   20074523
Adiposity regulation (4) S6kII Decreased triglyceride expression -0.53   20074523
Adiposity regulation (5) S6kII none -0.132   20074523
Blood cell homeostasis regulation (1) S6kII none np   20540764
Blood cell homeostasis regulation (2) S6kII none np   20540764
Actin organization and cell morphology (1) S6kII none np   19265526
Actin organization and cell morphology (2) S6kII none np   19265526
Actin organization and cell morphology (3) S6kII none np   19265526
Actin organization and cell morphology (4) S6kII none np   19265526
Actin organization and cell morphology (5) S6kII none np   19265526
Actin organization and cell morphology (6) S6kII none np   19265526
Vaccinia virus infection S6kII none sp   20585561
RTK-Ras-ERK pathway regulation (1) S6kII none 0.41 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) S6kII none 0.31 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) S6kII none -0.03 30 minutes sSpitz stimulation 22028469

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