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Protein : FBpp0087679 D. melanogaster

Primary Accession  ? Q7K105 Organism . Name  Drosophila melanogaster
MD5 Checksum  365b836c3473ca0db1e6d166be040c07 UniProt Accession  Q7K105
UniProt Name  Q7K105_DROME GenBank Identifier  AAF58953
Is UniProt Canonical  true Is Fragment  false
Length  537 Molecular Weight  61163
Name  Myd88 Secondary Identifier  FBpp0087679

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Uni Prot Comments Displayer

Protein Sequence Displayer


1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0033402 CG2078 Myd88 Myd88 FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


Cytoscape Network Displayer



0 Components

3 Cross References

Source . Name

Subject . Primary Identifier
NP_001260821.1 RefSeq FBpp0087679
Dm.2113 UniGene FBpp0087679
NP_610479.1 RefSeq FBpp0087679

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set
Reactome data set  

0 Ec Numbers

2 Locations

Located On . Primary Identifier
Start End Strand
2R 5191402 5195299 -1
2R 5191402 5195299 -1

34 Pathways

Identifier Name
105951 Immune System
88681 Innate Immune System
34578 TRAF6 Mediated Induction of proinflammatory cytokines
113278 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
112247 Cytokine Signaling in Immune system
167467 DEx/H-box helicases activate type I IFN and inflammatory cytokines production
120387 RIP-mediated NFkB activation via ZBP1
120480 ZBP1(DAI) mediated induction of type I IFNs
120468 Cytosolic sensors of pathogen-associated DNA
131727 TRAF6 mediated NF-kB activation
139163 RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
112945 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
29229 NOD1/2 Signaling Pathway
91838 Toll Like Receptor TLR1:TLR2 Cascade
109018 Toll Like Receptor 2 (TLR2) Cascade
85024 Toll Like Receptor TLR6:TLR2 Cascade
32391 Toll Like Receptor 9 (TLR9) Cascade
101443 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
92018 MyD88:Mal cascade initiated on plasma membrane
90914 Activated TLR4 signalling
109895 Toll Like Receptor 4 (TLR4) Cascade
87458 MyD88 dependent cascade initiated on endosome
79068 Toll Like Receptor 7/8 (TLR7/8) Cascade
30810 Toll Like Receptor 5 (TLR5) Cascade
91529 Toll-Like Receptors Cascades
143441 Trafficking and processing of endosomal TLR
99649 Toll Like Receptor 3 (TLR3) Cascade
99643 MyD88-independent cascade
34570 TRIF-mediated TLR3/TLR4 signaling
92313 Toll Like Receptor 10 (TLR10) Cascade

2 Protein Domains

DB identifier Name Short Name Type
IPR011029 Death-like domain DEATH-like_dom Domain
IPR000157 Toll/interleukin-1 receptor homology (TIR) domain TIR_dom Domain

2 Transcripts

DB identifier Gene
FBtr0088598 Myd88
FBtr0333000 Myd88