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Protein : FBpp0077011 D. melanogaster

Primary Accession  ? Q9V3Q6 Organism . Name  Drosophila melanogaster
MD5 Checksum  6473dbbeb22cdd7d67e209f6c23c5b6a UniProt Accession  Q9V3Q6
UniProt Name  M3K7_DROME GenBank Identifier  AAF50895
Is UniProt Canonical  true Is Fragment  false
Length  678 Molecular Weight  75675
Name  Mitogen-activated protein kinase kinase kinase 7 Secondary Identifier  FBpp0077011

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Genomics

1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0026323 CG18492 Tak1 TGF-beta activated kinase 1 FlyBase D. melanogaster

Proteins

Protein --> Gene + chromosomal location and length of the gene.

Interactions

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Other

0 Components

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
Dm.6425 UniGene FBpp0077011
NP_524080.1 RefSeq FBpp0077011

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Reactome data set  

1 Ec Numbers

Identifier Description
2.7.11.25  

1 Locations


Located On . Primary Identifier
Start End Strand
X 20387331 20394994 -1

31 Pathways

Identifier Name
105951 Immune System
88681 Innate Immune System
34578 TRAF6 Mediated Induction of proinflammatory cytokines
113278 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
87442 activated TAK1 mediates p38 MAPK activation
139259 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
82500 MAP kinase activation in TLR cascade
112247 Cytokine Signaling in Immune system
112945 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
29229 NOD1/2 Signaling Pathway
91838 Toll Like Receptor TLR1:TLR2 Cascade
109018 Toll Like Receptor 2 (TLR2) Cascade
85024 Toll Like Receptor TLR6:TLR2 Cascade
32391 Toll Like Receptor 9 (TLR9) Cascade
128412 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
101443 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
92018 MyD88:Mal cascade initiated on plasma membrane
90914 Activated TLR4 signalling
109895 Toll Like Receptor 4 (TLR4) Cascade
87458 MyD88 dependent cascade initiated on endosome
79068 Toll Like Receptor 7/8 (TLR7/8) Cascade
30810 Toll Like Receptor 5 (TLR5) Cascade
91529 Toll-Like Receptors Cascades
99649 Toll Like Receptor 3 (TLR3) Cascade
99643 MyD88-independent cascade
34570 TRIF-mediated TLR3/TLR4 signaling
92313 Toll Like Receptor 10 (TLR10) Cascade
81183 MyD88 cascade initiated on plasma membrane
145760 IRAK2 mediated activation of TAK1 complex
88280 Signaling by Interleukins

5 Protein Domains

DB identifier Name Short Name Type
IPR011009 Protein kinase-like domain Kinase-like_dom Domain
IPR000719 Protein kinase domain Prot_kinase_dom Domain
IPR017441 Protein kinase, ATP binding site Protein_kinase_ATP_BS Binding_site
IPR008271 Serine/threonine-protein kinase, active site Ser/Thr_kinase_AS Active_site
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain Ser-Thr/Tyr_kinase_cat_dom Domain

1 Transcripts

DB identifier Gene
FBtr0077319 Tak1