Genomics
Gene Ontology Displayer
Homologue Displayer
Mod Mine G Browse Displayer
Overlapping Features Displayer
Regulatory Regions Displayer
7 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0192598 | eIF4E-6[EY20966] | Drosophila melanogaster | |
| FBal0187216 | eIF4E-6[c03117] | Drosophila melanogaster | |
| FBal0187215 | eIF4E-6[f06737] | Drosophila melanogaster | |
| FBal0209478 | eIF4E-6[GD8319] | Drosophila melanogaster | |
| FBal0226380 | eIF4E-6[c02973] | Drosophila melanogaster | |
| FBal0226381 | eIF4E-6[c02689a] | Drosophila melanogaster | |
| FBal0226382 | eIF4E-6[c05147a] | Drosophila melanogaster |
4 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0039622:4 | eIF4E-6:4 |
| FBgn0039622:2 | eIF4E-6:2 |
| FBgn0039622:3 | eIF4E-6:3 |
| FBgn0039622:1 | eIF4E-6:1 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0085344-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0302515-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0302516-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085344-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0302515-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0302516-3-prime-utr | Drosophila melanogaster |
Other
71 Pathways
- Interferon Signaling,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Cytokine Signaling in Immune system,
- TOR signaling pathway,
- Deadenylation of mRNA,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Formation of a pool of free 40S subunits,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- RNA Polymerase II Pre-transcription Events,
- Insulin signaling pathway,
- RNA Pol II CTD phosphorylation and interaction with CE,
- IRS-mediated signalling,
- Metabolism of RNA,
- Immune System,
- IGF1R signaling cascade,
- Metabolism of mRNA,
- 3' -UTR-mediated translational regulation,
- Processing of Capped Intron-Containing Pre-mRNA,
- IRS activation,
- Metabolism of proteins,
- SLBP independent Processing of Histone Pre-mRNAs,
- Transport of the SLBP independent Mature mRNA,
- Ribosomal scanning and start codon recognition,
- Insulin receptor signalling cascade,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Transcription,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Deadenylation-dependent mRNA decay,
- Regulation of Rheb GTPase activity by AMPK,
- Cleavage of Growing Transcript in the Termination Region,
- Processing of Intronless Pre-mRNAs,
- mTOR signalling,
- Antiviral mechanism by IFN-stimulated genes,
- Release of eIF4E,
- Translation initiation complex formation,
- Insulin receptor mediated signaling,
- Regulation of AMPK activity via LKB1,
- Processing of Capped Intronless Pre-mRNA,
- ISG15 antiviral mechanism,
- RNA Polymerase II Transcription Initiation,
- Post-Elongation Processing of the Transcript,
- Insulin receptor recycling,
- Transport of Mature Transcript to Cytoplasm,
- IRS-related events triggered by IGF1R,
- Transport of the SLBP Dependant Mature mRNA,
- RNA Polymerase II Transcription Elongation,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- RNA Polymerase II Transcription,
- Post-Elongation Processing of Intronless pre-mRNA,
- IRS-related events,
- PI3K Cascade,
- RNA Polymerase II Promoter Escape,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- PKB-mediated events,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- mRNA Processing,
- Gene Expression,
- RNA Polymerase II Transcription Termination,
- Translation,
- mRNA Capping,
- Formation of the Early Elongation Complex,
- Eukaryotic Translation Initiation,
- Signaling Pathways,
- Elongation arrest and recovery,
- DINR-mediated activation,
- Formation of RNA Pol II elongation complex,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- mTORC1-mediated signalling,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Cap-dependent Translation Initiation
1 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43422 | NCBI Entrez Gene identifiers | FBgn0039622 |
9 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
13 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | eIF4E-6 | none | 0.748765323 | 19067489 | |
| Lipid storage | eIF4E-6 | none | 1.162662267 | 19067489 | |
| Cell size and cell-cycle regulation (1) | eIF4E-6 | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | eIF4E-6 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | eIF4E-6 | Lethal | np | 20220848 | |
| Heat nociception (1) | eIF4E-6 | Developmentally lethal | 0 | 21074052 | |
| Heat nociception (1) | eIF4E-6 | none | -0.58 | 21074052 | |
| Heart development and function (1) | eIF4E-6 | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | eIF4E-6 | none | -0.796875 | 19520911 | |
| Notch pathway regulation (4) | eIF4E-6 | Loss of bristles, notum malformation death | sp | 19363474 | |
| Notch pathway regulation (4) | eIF4E-6 | Colour defects, bristle morphology defects, notum malformation death | sp | 19363474 | |
| Adiposity regulation (1) | eIF4E-6 | none | 0.103 | 20074523 | |
| Hippo pathway regulation | eIF4E-6 | none | -0.7 | 23263283 |
