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Gene : eIF4E-4 D. melanogaster

DB identifier  ? FBgn0035709 Secondary Identifier  ? CG10124
Name  ? eIF4E-4 Source  FlyBase
  • synonyms:
  • CG10124,
  • NEST:bs04e06,
  • eIF4E,
  • FBan0010124,
  • CT28485,
  • FBgn0045411,
  • FBgn0035709,
  • BEST:GH01027,
  • FBgn0046310

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2 Alleles

DB identifier Symbol Allele Class Organism
FBal0214940 eIF4E-4[GD6700]   Drosophila melanogaster
FBal0233587 eIF4E-4[KK105485]   Drosophila melanogaster

30 Clones

Secondary Identifier DB identifier
DPiM_GH23527 FBcl0740646
AT01366 FBcl0024595
AT21815 FBcl0024607
AT31928 FBcl0024609
AT30420 FBcl0024613
AT31045 FBcl0024615
AT07617 FBcl0024617
AT09989 FBcl0024619
AT09177 FBcl0024621
AT20421 FBcl0024623
AT23151 FBcl0024625
AT28378 FBcl0024627
bs68a03 FBcl0052291
bs74d11 FBcl0052293
bs49b09 FBcl0052295
bs47f10 FBcl0052297
bs84h08 FBcl0052301
bs32d08 FBcl0052303
bs56a04 FBcl0052305
bs65b01 FBcl0052307
bs66a11 FBcl0052309
bs83g12 FBcl0052311
bs12g07 FBcl0052313
bs15c08 FBcl0052325
EC03316 FBcl0067917
GH21865 FBcl0109805
GH01027 FBcl0109847
GH23527 FBcl0109863
LP19770 FBcl0182168
180977 FBcl0475820

4 Exons

DB identifier Symbol
FBgn0035709:4 eIF4E-4:4
FBgn0035709:3 eIF4E-4:3
FBgn0035709:2 eIF4E-4:2
FBgn0035709:1 eIF4E-4:1

1 Transcripts

DB identifier Gene
FBtr0076963 eIF4E-4

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076963-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076963-3-prime-utr Drosophila melanogaster

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71 Pathways

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38743 NCBI Entrez Gene identifiers FBgn0035709

9 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 248.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 80.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 88.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 59.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 125.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 48.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 133.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 85.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 58.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 80.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 58.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 35.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 52.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 19.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 107.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 517.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 45.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 122.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 67.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 63.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 127.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 52.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 235.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 189.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 21.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 152.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 395.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 86.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 49.0
FBgn0035709 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 8.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0035709:4_FBgn0035709:3 Drosophila melanogaster
intron_FBgn0035709:3_FBgn0035709:2 Drosophila melanogaster
intron_FBgn0035709:2_FBgn0035709:1 Drosophila melanogaster

10 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eIF4E-4 none 2.824689431   19067489
Lipid storage eIF4E-4 none 0.724673597   19067489
ERK signaling eIF4E-4 ERK activation reduced weak   17086199
Cell size and cell-cycle regulation (1) eIF4E-4 none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) eIF4E-4 Synthetic lethal with methyl methanesulphonate sp   19543366
RTK-Ras-ERK pathway regulation (1) eIF4E-4 Decreased ERK phosphorylation after EGF stimulation -2.34 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) eIF4E-4 none -0.99 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF4E-4 none -0.43 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF4E-4 none -1.44 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation eIF4E-4 none 0.82   23263283

0 Submissions