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Gene : hay D. melanogaster

DB identifier  ? FBgn0001179 Secondary Identifier  ? CG8019
Name  ? haywire Source  FlyBase
  • synonyms:
  • XPB,
  • FBgn0001179,
  • DhXPB,
  • i50,
  • DhR25,
  • DmXPB,
  • ms(3)nc2,
  • Haywire,
  • CG8019,
  • Xpb/hay,
  • FBan0008019,
  • Hay,
  • nc2,
  • FBgn0004376,
  • FBgn0015830,
  • ERCC3,
  • hwr,
  • TFIIH

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30 Alleles

DB identifier Symbol Allele Class Organism
FBal0159173 hay[f00028]   Drosophila melanogaster
FBal0257010 hay[Scer\UAS.cMa]   Drosophila melanogaster
FBal0039390 hay[B]   Drosophila melanogaster
FBal0034768 hay[+t7.8]   Drosophila melanogaster
FBal0031455 hay[A17T,G23A]   Drosophila melanogaster
FBal0031458 hay[hs.P]   Drosophila melanogaster
FBal0096903 hay[nc2.tMa]   Drosophila melanogaster
FBal0005390 hay[nc2rv6] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0150438 hay[XPCS.Hsp83]   Drosophila melanogaster
FBal0150439 hay[TTD.Hsp83]   Drosophila melanogaster
FBal0118213 hay[unspecified]   Drosophila melanogaster
FBal0031457 hay[E(z)66]   Drosophila melanogaster
FBal0005391 hay[nc2rv7] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0005386 hay[nc2rv2] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0005389 hay[nc2rv5] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0031462 hay[nc2rvP18]   Drosophila melanogaster
FBal0031459 hay[nc2rv12]   Drosophila melanogaster
FBal0096904 hay[WT.e11] wild-type allele Drosophila melanogaster
FBal0096905 hay[WT.A244P] wild-type allele Drosophila melanogaster
FBal0005388 hay[nc2rv4] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0031460 hay[nc2rv8]   Drosophila melanogaster
FBal0005384 hay[nc2] antimorphic allele - genetic evidence, temperature conditional hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0096906 hay[WT.A238T] wild-type allele Drosophila melanogaster
FBal0147104 hay[dsRNA.cCa]   Drosophila melanogaster
FBal0005387 hay[nc2rv3] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0031461 hay[nc2rv9]   Drosophila melanogaster
FBal0005385 hay[nc2rv1] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0031456 hay[E(z)65]   Drosophila melanogaster
FBal0209674 hay[GD4213]   Drosophila melanogaster
FBal0230934 hay[KK100816]   Drosophila melanogaster

36 Clones

Secondary Identifier DB identifier
EC14954 FBcl0064385
EP11061 FBcl0078213
EK176547 FBcl0098136
EK199932 FBcl0098238
LD44022 FBcl0169135
RE25115 FBcl0210253
RE53305 FBcl0210276
RE05247 FBcl0210284
RE38779 FBcl0210290
RE59011 FBcl0210309
RE63003 FBcl0210310
UT01631 FBcl0292599
FI01118 FBcl0383810
EC055676 FBcl0303060
EC056091 FBcl0303057
EC053649 FBcl0303058
EC053652 FBcl0303059
RP004251622 FBcl0673808
RP004144584 FBcl0673809
RP004494661 FBcl0673810
RP004146223 FBcl0673811
RP004206685 FBcl0673812
RP004199947 FBcl0673813
RP004391195 FBcl0673814
RP004143940 FBcl0673815
RP004236619 FBcl0673816
RP004496123 FBcl0673817
RP004451034 FBcl0673818
RP004481861 FBcl0673819
RP004542033 FBcl0673820

5 Exons

DB identifier Symbol
FBgn0001179:1 hay:1
FBgn0001179:3 hay:3
FBgn0001179:4 hay:4
FBgn0001179:5 hay:5
FBgn0001179:2 hay:2

2 Transcripts

DB identifier Gene
FBtr0114599 hay
FBtr0076253 hay

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076253-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0114599-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076253-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0114599-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39202 NCBI Entrez Gene identifiers FBgn0001179
64581 BioGRID FBgn0001179

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 800.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 747.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 599.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 849.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1056.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 349.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 620.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 727.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 344.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 894.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 700.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 526.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 602.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 491.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 503.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 764.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1247.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 730.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1047.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1049.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 909.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 834.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1218.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 578.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 747.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1346.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 756.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1076.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 666.0
FBgn0001179 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 524.0

4 Introns

DB identifier
Organism . Name
intron_FBgn0001179:2_FBgn0001179:4 Drosophila melanogaster
intron_FBgn0001179:4_FBgn0001179:5 Drosophila melanogaster
intron_FBgn0001179:1_FBgn0001179:3 Drosophila melanogaster
intron_FBgn0001179:3_FBgn0001179:4 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage hay none 0.361683162   19067489
Lipid storage hay none -0.040123694   19067489
Multipolar division hay Centrosome clustering defects strong   18662975
Chlamydia caviae infection hay Decreased Chlamydia caviae infection np   17967059
Alternative splicing hay Alternative Dscam (exon 4) splicing sp   15492211
Constitutive protein secretion and Golgi organization (1) hay Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) hay none sp   16496002
Dendrite pattern formation hay none np   16547170
Combinatorial effect with methyl methanesulphonate (1) hay none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) hay Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation hay Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) hay none np   20220848
Muscle morphogenesis and function (1) hay none np   20220848
Heat nociception (1) hay none 1.5   21074052
Heart development and function (1) hay none 1   20371351
Serratia marcescens infection (1) hay none 0.721649484536082   19520911
Serratia marcescens infection (1) hay Increased viability after Serratia marcescens infection 2.19117647058823   19520911
Serratia marcescens infection (2) hay Increased viability after Serratia marcescens infection sp   19520911
Serratia marcescens infection (4) hay Increased viability after Serratia marcescens infection sp   19520911
Notch pathway regulation (4) hay Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation hay Increased P-JNK protein expression with PGN 1.97 15 min PGN induction 19893628
Toll-dependent innate immune pathway regulation hay Downregulation of Toll pathway after hEGF stimulation -3.2   20375635
Pol II elongation hay Decreased Hsp70 mRNA expression 61 20 min heat shock 19279664
Notch pathway regulation (1) hay Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) hay none np en-GAL4 20493818
Notch pathway regulation (2) hay Downregulation of Notch pathway; wing disc NRE:EGFP: down; wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (3) hay none np   20493818
Adiposity regulation (1) hay none -0.439   20074523
Adiposity regulation (1) hay none 0.108   20074523
RTK-Ras-ERK pathway regulation (1) hay none 0.47 10 minutes EGF stimulation 22028469

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