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Gene : mle D. melanogaster

DB identifier  ? FBgn0002774 Secondary Identifier  ? CG11680
Name  ? maleless Source  FlyBase
  • synonyms:
  • Maleless,
  • mak,
  • no-action-potential,
  • mls,
  • no action potential,
  • nap,
  • MLE,
  • mll,
  • male-killer,
  • FBgn0002774,
  • CG11680,
  • FBan0011680,
  • male-lethal,
  • maleless-no-action potential,
  • nap[ts],
  • male lethal

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58 Alleles

DB identifier Symbol Allele Class Organism
FBal0158939 mle[e04702]   Drosophila melanogaster
FBal0280405 mle[Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0280406 mle[DeltaRB1.Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0280407 mle[DeltaRB2.Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0280408 mle[Delta1,2.Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0280409 mle[DeltaG.Hsp83.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0023799 mle[nap-ts2] heat sensitive gain of function allele Drosophila melanogaster
FBal0269853 mle[DeltaMTAD]   Drosophila melanogaster
FBal0269854 mle[+t10.2]   Drosophila melanogaster
FBal0012332 mle[1] loss of function allele Drosophila melanogaster
FBal0035222 mle[+t10.5]   Drosophila melanogaster
FBal0012343 mle[10]   Drosophila melanogaster
FBal0056488 mle[hs.PR]   Drosophila melanogaster
FBal0061054 mle[GET]   Drosophila melanogaster
FBal0154955 mle[Z1536]   Drosophila melanogaster
FBal0012346 mle[13]   Drosophila melanogaster
FBal0012335 mle[2]   Drosophila melanogaster
FBal0012345 mle[12]   Drosophila melanogaster
FBal0012339 mle[6]   Drosophila melanogaster
FBal0154953 mle[Z5317]   Drosophila melanogaster
FBal0012348 mle[15]   Drosophila melanogaster
FBal0023804 mle[nap-ts7] gain of function allele Drosophila melanogaster
FBal0012334 mle[1b]   Drosophila melanogaster
FBal0023801 mle[nap-ts4] heat sensitive gain of function allele Drosophila melanogaster
FBal0012338 mle[5]   Drosophila melanogaster
FBal0012333 mle[1a]   Drosophila melanogaster
FBal0056501 mle[unspecified]   Drosophila melanogaster
FBal0023805 mle[nap-rv1] gain of function allele Drosophila melanogaster
FBal0127935 mle[dsRNA.N]   Drosophila melanogaster
FBal0012342 mle[9] loss of function allele Drosophila melanogaster

19 Clones

Secondary Identifier DB identifier
EK040455 FBcl0064954
EK243041 FBcl0064984
EK162334 FBcl0065018
GM25238 FBcl0145773
HL02337 FBcl0150255
LD41112 FBcl0175270
LD44547 FBcl0175273
RE21725 FBcl0227475
RE20562 FBcl0227492
RH17678 FBcl0266321
SD02678 FBcl0282720
SD18044 FBcl0282724
Dmel_neb_013843_0081_2688 FBcl0375818
Dmel_neb_013623_0395_0563 FBcl0375819
Dmel_neb_014912_0131_1727 FBcl0375820
CK01.50C.F10 FBcl0450698
105735 FBcl0450682
103333 FBcl0450677
45992 FBcl0450693

7 Exons

DB identifier Symbol
FBgn0002774:7 mle:7
FBgn0002774:6 mle:6
FBgn0002774:4 mle:4
FBgn0002774:3 mle:3
FBgn0002774:2 mle:2
FBgn0002774:5 mle:5
FBgn0002774:1 mle:1

2 Transcripts

DB identifier Gene
FBtr0086031 mle
FBtr0100576 mle

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086031-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0100576-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086031-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0100576-3-prime-utr Drosophila melanogaster

Interactions

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Other

39 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35523 NCBI Entrez Gene identifiers FBgn0002774
61429 BioGRID FBgn0002774

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 568.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 551.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 513.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 541.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 573.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 243.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 767.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 436.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 423.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 661.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 397.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 507.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 475.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 639.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 393.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 447.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 576.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 651.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 495.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 469.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 617.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 652.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 529.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 478.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 624.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 634.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 576.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 885.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 675.0
FBgn0002774 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 627.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0002774:7_FBgn0002774:6 Drosophila melanogaster
intron_FBgn0002774:6_FBgn0002774:4 Drosophila melanogaster
intron_FBgn0002774:4_FBgn0002774:3 Drosophila melanogaster
intron_FBgn0002774:3_FBgn0002774:2 Drosophila melanogaster
intron_FBgn0002774:5_FBgn0002774:4 Drosophila melanogaster
intron_FBgn0002774:3_FBgn0002774:1 Drosophila melanogaster

12 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage mle none -0.084273126   19067489
Lipid storage mle none 1.052571215   19067489
Alternative splicing mle none sp   15492211
Cell size and cell-cycle regulation (1) mle none sp   16496002
Cell size and cell-cycle regulation (1) mle none sp   16496002
Muscle morphogenesis and function (1) mle none np   20220848
Heat nociception (1) mle none -1.17   21074052
Heart development and function (1) mle none 1   20371351
Serratia marcescens infection (1) mle none 1   19520911
Notch pathway regulation (4) mle none 0   19363474
Adiposity regulation (1) mle none -0.179   20074523
Hippo pathway regulation mle none -0.36   23263283

0 Submissions