modENCODE |  Help |  blog

Gene : eIF4G D. melanogaster

DB identifier  ? FBgn0023213 Secondary Identifier  ? CG10811
Name  ? eukaryotic translation initiation factor 4G Source  FlyBase
  • synonyms:
  • FBgn0023213,
  • Eukaryotic-initiation-factor-4G,
  • CG10811,
  • translation initiation factor,
  • deIF4G,
  • Eukaryotic initiation factor 4G,
  • eIF-4G,
  • p200,
  • EIF4G,
  • FBan0010811,
  • translation initiation factor eIF4G

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

5 Alleles

DB identifier Symbol Allele Class Organism
FBal0257445 eIF4G[HMS00762]   Drosophila melanogaster
FBal0261861 eIF4G[CPTI002576]   Drosophila melanogaster
FBal0134105 eIF4G[dsRNA.cHa]   Drosophila melanogaster
FBal0180055 eIF4G[e02087]   Drosophila melanogaster
FBal0209482 eIF4G[GD7098]   Drosophila melanogaster

124 Clones

Secondary Identifier DB identifier
FI02056 FBcl0481791
ESG0117c.B21_B12 FBcl0003263
EK240942 FBcl0011468
EK073640 FBcl0011720
EK288036 FBcl0013468
EK047842 FBcl0013694
EK065939 FBcl0014206
EK216626 FBcl0014350
EK241311 FBcl0014436
EK089557 FBcl0015718
EK188043 FBcl0015848
EK236247 FBcl0015866
EK076142 FBcl0015910
EK087458 FBcl0015978
EK081557 FBcl0016002
EK225552 FBcl0016044
EK217317 FBcl0016064
EK151529 FBcl0016104
EK065641 FBcl0016148
EK250560 FBcl0016168
EK034831 FBcl0016188
EK160361 FBcl0016254
EK252609 FBcl0016360
EK039456 FBcl0016404
EK245128 FBcl0016644
EK140464 FBcl0016664
EK252817 FBcl0016686
EK257038 FBcl0016772
EK157708 FBcl0016792
EK057553 FBcl0016816

18 Exons

DB identifier Symbol
FBgn0023213:18 eIF4G:18
FBgn0023213:16 eIF4G:16
FBgn0023213:15 eIF4G:15
FBgn0023213:13 eIF4G:13
FBgn0023213:12 eIF4G:12
FBgn0023213:11 eIF4G:11
FBgn0023213:10 eIF4G:10
FBgn0023213:9 eIF4G:9
FBgn0023213:8 eIF4G:8
FBgn0023213:7 eIF4G:7
FBgn0023213:6 eIF4G:6
FBgn0023213:5 eIF4G:5
FBgn0023213:4 eIF4G:4
FBgn0023213:2 eIF4G:2
FBgn0023213:3 eIF4G:3
FBgn0023213:1 eIF4G:1
FBgn0023213:14 eIF4G:14
FBgn0023213:17 eIF4G:17

3 Transcripts

DB identifier Gene
FBtr0112904 eIF4G
FBtr0089243 eIF4G
FBtr0289951 eIF4G

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0089243-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112904-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0289951-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089243-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112904-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0289951-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

76 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43839 NCBI Entrez Gene identifiers FBgn0023213
68664 BioGRID FBgn0023213

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 5437.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 4924.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 6467.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2351.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 6769.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3963.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 5862.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 6154.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 3927.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 7741.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 9773.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 7238.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 5781.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 4389.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 5118.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 8182.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 7628.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 5623.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 4784.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 6850.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5972.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 9673.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 6378.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 6635.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 5381.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 11851.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 4698.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 6108.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 6120.0
FBgn0023213 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 7402.0

18 Introns

DB identifier
Organism . Name
intron_FBgn0023213:18_FBgn0023213:16 Drosophila melanogaster
intron_FBgn0023213:16_FBgn0023213:15 Drosophila melanogaster
intron_FBgn0023213:15_FBgn0023213:13 Drosophila melanogaster
intron_FBgn0023213:13_FBgn0023213:12 Drosophila melanogaster
intron_FBgn0023213:12_FBgn0023213:11 Drosophila melanogaster
intron_FBgn0023213:11_FBgn0023213:10 Drosophila melanogaster
intron_FBgn0023213:10_FBgn0023213:9 Drosophila melanogaster
intron_FBgn0023213:9_FBgn0023213:8 Drosophila melanogaster
intron_FBgn0023213:8_FBgn0023213:7 Drosophila melanogaster
intron_FBgn0023213:7_FBgn0023213:6 Drosophila melanogaster
intron_FBgn0023213:6_FBgn0023213:5 Drosophila melanogaster
intron_FBgn0023213:5_FBgn0023213:4 Drosophila melanogaster
intron_FBgn0023213:4_FBgn0023213:3 Drosophila melanogaster
intron_FBgn0023213:3_FBgn0023213:2 Drosophila melanogaster
intron_FBgn0023213:2_FBgn0023213:1 Drosophila melanogaster
intron_FBgn0023213:15_FBgn0023213:14 Drosophila melanogaster
intron_FBgn0023213:14_FBgn0023213:13 Drosophila melanogaster
intron_FBgn0023213:17_FBgn0023213:16 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage eIF4G Increased lipid droplet area 6.400363835   19067489
Lipid storage eIF4G Increased lipid droplet area 5.320682683   19067489
ERK signaling eIF4G ERK activation reduced weak   17086199
Cell size and cell-cycle regulation (1) eIF4G none sp   16496002
Cell size and cell-cycle regulation (1) eIF4G Increased G1 DNA content, decreased G2 DNA content, decreased G1 cell size sp   16496002
Cell size and cell-cycle regulation (2) eIF4G none 1.236   16496002
Cell size and cell-cycle regulation (3) eIF4G none 431   16496002
Microtubule assembly and organization eIF4G Abnormal spindle, monopolar spindle, increased number of cells in prometaphase np   18463163
Mutant human huntingtin aggregation eIF4G Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) eIF4G Lethal np   20220848
Muscle morphogenesis and function (1) eIF4G Lethal np   20220848
Muscle morphogenesis and function (3) eIF4G Split myofibril, fading Z-line np   20220848
Heat nociception (1) eIF4G none -1.17   21074052
Heat nociception (1) eIF4G none -1.17   21074052
Heart development and function (1) eIF4G none 1   20371351
Serratia marcescens infection (1) eIF4G none -0.655913978494623   19520911
Serratia marcescens infection (1) eIF4G none -0.487179487179487   19520911
Notch pathway regulation (4) eIF4G Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) eIF4G Completely lethal (before pupal) sp   19363474
G2-M DNA damage checkpoint regulation (2) eIF4G Increased histone H3 phosphorylation with bleocin 31.11 with bleocin 21205937
G2-M DNA damage checkpoint regulation (2) eIF4G Increased histone H3 phosphorylation with doxorubicin 31.4 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) eIF4G Increased histone H3 phosphorylation with etoposide 49.62 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) eIF4G Increased histone H3 phosphorylation after X-ray exposure 69.74 X-ray exposure 21205937
Adiposity regulation (1) eIF4G none -0.042   20074523
Adiposity regulation (1) eIF4G none 0.103   20074523
RTK-Ras-ERK pathway regulation (1) eIF4G Decreased ERK phosphorylation after EGF stimulation -2.41 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) eIF4G none -1.4 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF4G none -0.53 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) eIF4G none -1.07 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation eIF4G none 0.35   23263283

0 Submissions