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Gene : Ef1alpha48D D. melanogaster

DB identifier  ? FBgn0000556 Secondary Identifier  ? CG8280
Name  ? Elongation factor 1alpha48D Source  FlyBase
  • synonyms:
  • EF-1alpha F1,
  • EF-1[a],
  • 1275,
  • F1,
  • Elongation factor 1 alpha 48D,
  • Translational elongation factor1,
  • Dm0084,
  • Ef1a10,
  • eEF1alpha,
  • DmEF1,
  • EF-1alphaF[[1]],
  • anon-EST:Liang-2.46,
  • l(2)01275,
  • Ef1alpha1,
  • EF11_DROME,
  • EF1alpha48D,
  • anon-EST:Liang-1.17,
  • EF-1alphaF,
  • FBan0008280,
  • clone 2.46,
  • elongation factor 1-alpha F1,
  • EF-1,
  • EF,
  • EF1-alpha,
  • l(2)k07303,
  • EF-1a,
  • l(2)1275,
  • EF-1alpha,
  • Elongation factor 1alpha48D,
  • clone 1.17,
  • FBgn0010480,
  • FBgn0000556,
  • EF1alpha 48D,
  • EF1alpha,
  • Ef1alpha48E,
  • Ef1a48D,
  • F1 EF-1alpha,
  • Efalpha48D,
  • FBgn0022092,
  • EF-1alphaF1,
  • CG8280,
  • Elongation factor 1 alpha

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Regulatory Regions Displayer

21 Alleles

DB identifier Symbol Allele Class Organism
FBal0183729 Ef1alpha48D[d08476]   Drosophila melanogaster
FBal0064394 Ef1alpha48D[k07303]   Drosophila melanogaster
FBal0257590 Ef1alpha48D[HMS00917]   Drosophila melanogaster
FBal0160514 Ef1alpha48D[EY09615]   Drosophila melanogaster
FBal0065258 Ef1alpha48D[k17014]   Drosophila melanogaster
FBal0065259 Ef1alpha48D[k10501]   Drosophila melanogaster
FBal0065260 Ef1alpha48D[k07507]   Drosophila melanogaster
FBal0065261 Ef1alpha48D[k06102]   Drosophila melanogaster
FBal0007966 Ef1alpha48D[01275]   Drosophila melanogaster
FBal0043374 Ef1alpha48D[04829]   Drosophila melanogaster
FBal0238970 Ef1alpha48D[G13120]   Drosophila melanogaster
FBal0033659 Ef1alpha48D[hs.PS]   Drosophila melanogaster
FBal0156492 Ef1alpha48D[BSC25]   Drosophila melanogaster
FBal0287092 Ef1alpha48D[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287093 Ef1alpha48D[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0206944 Ef1alpha48D[GD13875]   Drosophila melanogaster
FBal0206945 Ef1alpha48D[GD17848]   Drosophila melanogaster
FBal0226349 Ef1alpha48D[CB-5508-3]   Drosophila melanogaster
FBal0226350 Ef1alpha48D[CB-6286-3]   Drosophila melanogaster
FBal0226351 Ef1alpha48D[d10427]   Drosophila melanogaster
FBal0236297 Ef1alpha48D[KK109406]   Drosophila melanogaster

2127 Clones

Secondary Identifier DB identifier
ESG019c.E21_B08 FBcl0000018
ESG0118d.B21_C08 FBcl0001913
ESG0116d.B21_C01 FBcl0002349
ESG0116b.B21_E06 FBcl0002753
ESG0118c.B21_F02 FBcl0002795
ESG017c.E21.3_E06 FBcl0006469
ESG0114c.B21_E10 FBcl0006635
ESG014d.E21_F04 FBcl0007309
ESG0115c.B21_B12 FBcl0007823
ESG014d.E21_H07 FBcl0007997
ESG015c.E21_H01 FBcl0008177
ESG015d.B21.1_F11 FBcl0008417
ESG015b.E21_A09 FBcl0008761
ESG014a.E21_B12 FBcl0011141
EK043030 FBcl0089842
EK189521 FBcl0090080
EK129162 FBcl0090378
EK225836 FBcl0090558
EN03745 FBcl0096243
GH26262 FBcl0133863
GH07047 FBcl0133871
GH03724 FBcl0133875
GH26655 FBcl0133883
GH14171 FBcl0133889
GH14229 FBcl0133971
GH11205 FBcl0133987
GH05138 FBcl0134093
GH09085 FBcl0134119
GH06080 FBcl0134147
GH06408 FBcl0134163

4 Exons

DB identifier Symbol
FBgn0000556:2 Ef1alpha48D:2
FBgn0000556:3 Ef1alpha48D:3
FBgn0000556:1 Ef1alpha48D:1
FBgn0000556:4 Ef1alpha48D:4

2 Transcripts

DB identifier Gene
FBtr0088035 Ef1alpha48D
FBtr0331927 Ef1alpha48D

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0088035-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331927-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0088035-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331927-3-prime-utr Drosophila melanogaster

Interactions

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Other

40 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36271 NCBI Entrez Gene identifiers FBgn0000556
62056 BioGRID FBgn0000556

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 9970.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 9445.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 12957.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 11262.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 9371.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 27207.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 17536.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 21095.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 27408.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 16202.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 14410.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 24267.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 19367.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 26934.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 21891.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 25740.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 12012.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 18325.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 21429.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 13949.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 16396.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 14246.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 11964.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 9962.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 9618.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 9782.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 19923.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 17624.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 7709.0
FBgn0000556 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 4903.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0000556:2_FBgn0000556:3 Drosophila melanogaster
intron_FBgn0000556:1_FBgn0000556:4 Drosophila melanogaster

29 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Ef1alpha48D none 2.612759697   19067489
Lipid storage Ef1alpha48D none 0.693279812   19067489
Alternative splicing Ef1alpha48D none sp   15492211
L. monocytogenes infection Ef1alpha48D Fewer infected cells, less vacuolar escape, fewer bacteria per cell *   16157870
Constitutive protein secretion and Golgi organization (1) Ef1alpha48D Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Ef1alpha48D Increased G1 DNA content, decreased G2 DNA content, decreased G1 cell size sp   16496002
Cell size and cell-cycle regulation (1) Ef1alpha48D none sp   16496002
Cell size and cell-cycle regulation (2) Ef1alpha48D none 1.35   16496002
Cell size and cell-cycle regulation (3) Ef1alpha48D none 448   16496002
Mitochondrial biogenesis and function Ef1alpha48D Increased mitochondrial citrate synthase activity, decreased viability 1.334   18042644
Microtubule assembly and organization Ef1alpha48D none np   18463163
Combinatorial effect with methyl methanesulphonate (2) Ef1alpha48D none sp   19543366
Muscle morphogenesis and function (1) Ef1alpha48D Lethal np   20220848
Muscle morphogenesis and function (1) Ef1alpha48D Lethal np   20220848
Muscle morphogenesis and function (1) Ef1alpha48D Lethal np   20220848
Muscle morphogenesis and function (3) Ef1alpha48D Fading Z-line np   20220848
Heat nociception (1) Ef1alpha48D none -1.17   21074052
Heart development and function (1) Ef1alpha48D Pupal lethal 0   20371351
Serratia marcescens infection (1) Ef1alpha48D none -0.1   19520911
Notch pathway regulation (4) Ef1alpha48D Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Ef1alpha48D Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Ef1alpha48D Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation Ef1alpha48D Increased P-JNK protein expression with PGN 2.11 60 min PGN induction 19893628
Adiposity regulation (1) Ef1alpha48D none -0.225   20074523
RTK-Ras-ERK pathway regulation (1) Ef1alpha48D none 0.22 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Ef1alpha48D Decreased ERK phosphorylation after EGF stimulation -3.51 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Ef1alpha48D none -0.6 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Ef1alpha48D none -0.37 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Ef1alpha48D none 2.42   23263283

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