Genomics
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15 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0257206 | alc[HMS00316] | Drosophila melanogaster | |
| FBal0278642 | alc[GL01188] | Drosophila melanogaster | |
| FBal0262520 | alc[GL00029] | Drosophila melanogaster | |
| FBal0141869 | alc[cPa] | Drosophila melanogaster | |
| FBal0141870 | alc[a.cPa] | Drosophila melanogaster | |
| FBal0214862 | alc[GD12364] | Drosophila melanogaster | |
| FBal0216517 | alc[DP00037] | Drosophila melanogaster | |
| FBal0104541 | alc[Ad2] | Drosophila melanogaster | |
| FBal0221003 | alc[unspecified] | Drosophila melanogaster | |
| FBal0221004 | alc[K12] | Drosophila melanogaster | |
| FBal0221005 | alc[Delta12.125] | Drosophila melanogaster | |
| FBal0221006 | alc[Scer\UAS.cSa] | Drosophila melanogaster | |
| FBal0043573 | alc[1] | Drosophila melanogaster | |
| FBal0236230 | alc[KK109325] | Drosophila melanogaster | |
| FBal0275829 | alc[NIG.8057R] | Drosophila melanogaster |
60 Clones
4 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0260972:4 | alc:4 |
| FBgn0260972:2 | alc:2 |
| FBgn0260972:1 | alc:1 |
| FBgn0260972:3 | alc:3 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0088624-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0088625-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088624-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0088625-3-prime-utr | Drosophila melanogaster |
Other
27 Pathways
- IGF1R signaling cascade,
- TOR signaling pathway,
- Regulation of AMPK activity via LKB1,
- IRS-related events,
- Release of eIF4E,
- mTORC1-mediated signalling,
- Insulin receptor recycling,
- Metabolism,
- Fatty acid, triacylglycerol, and ketone body metabolism,
- IRS-related events triggered by IGF1R,
- DINR-mediated activation,
- Regulation of Rheb GTPase activity by AMPK,
- Insulin signaling pathway,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- mTOR signalling,
- Integration of energy metabolism,
- PKB-mediated events,
- Insulin receptor mediated signaling,
- IRS-mediated signalling,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Metabolism of lipids and lipoproteins,
- AMPK inhibits chREBP transcriptional activation activity,
- Import of palmitoyl-CoA into the mitochondrial matrix,
- IRS activation,
- PI3K Cascade,
- Insulin receptor signalling cascade,
- Signaling Pathways
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 35931 | NCBI Entrez Gene identifiers | FBgn0260972 |
| 61769 | BioGRID | FBgn0260972 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster |
17 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | alc | none | 0.051190842 | 19067489 | |
| Lipid storage | alc | none | 0.5584938 | 19067489 | |
| Lipid storage | alc | none | -0.005146519 | 19067489 | |
| Lipid storage | alc | none | -0.554306721 | 19067489 | |
| Lipid storage | alc | none | -0.482259886 | 19067489 | |
| Lipid storage | alc | none | -2.106553428 | 19067489 | |
| Intracellular Listeria monocytogenes infection | alc | Increased GFP protein expression | weak | 16020693 | |
| Cell size and cell-cycle regulation (1) | alc | none | sp | 16496002 | |
| Combinatorial effect with methyl methanesulphonate (2) | alc | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| PGN-induced dJNK phosphorylation | alc | Increased P-JNK protein expression with PGN | 3.31 | 15 min PGN induction | 19893628 |
| Vaccinia virus infection | alc | Decreased number of vaccinia virus infected cells | sp | 20585561 | |
| RTK-Ras-ERK pathway regulation (1) | alc | none | 0.38 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | alc | none | 0.22 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | alc | none | 0.26 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | alc | Decreased ERK phosphorylation after sSpitz and EGF stimulation | -1.55 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | alc | none | 0.12 | 23263283 | |
| Glycosylation regulation (1) | alc | none | sp | 21203496 |
