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Gene : Tm2 D. melanogaster

DB identifier  ? FBgn0004117 Secondary Identifier  ? CG4843
Name  ? Tropomyosin 2 Source  FlyBase
  • synonyms:
  • Ifm(3)5,
  • FBgn0026830,
  • tropomyosin 127,
  • Tm,
  • FBgn0004117,
  • DROTROPI1,
  • Tropomyosin,
  • FBgn0003724,
  • mTmI,
  • TM2,
  • lethal(3)nc99Eb,
  • Ifm(3)3,
  • FBgn0002442,
  • TmII,
  • tropomyosin2,
  • CG4843,
  • dro Tm,
  • Ifm-TmI,
  • Tn-H,
  • FBgn0003722,
  • Tropomyosin I,
  • TmI,
  • Tm1,
  • FBan0004843,
  • Tm127,
  • l(3)nc99Eb,
  • IP16005p,
  • Tropomyosin-2

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31 Alleles

DB identifier Symbol Allele Class Organism
FBal0245413 Tm2[JF01095]   Drosophila melanogaster
FBal0150582 Tm2[ZCL2456]   Drosophila melanogaster
FBal0016895 Tm2[3] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0051826 Tm2[hs.PS]   Drosophila melanogaster
FBal0051827 Tm2[5'.1B.2B.DeltaBgl]   Drosophila melanogaster
FBal0051828 Tm2[DeltaBgl]   Drosophila melanogaster
FBal0051829 Tm2[DeltaBgl.hs]   Drosophila melanogaster
FBal0051830 Tm2[DeltaBgl.3B]   Drosophila melanogaster
FBal0051831 Tm2[DeltaBgl.2B]   Drosophila melanogaster
FBal0051832 Tm2[DeltaBgl.1B]   Drosophila melanogaster
FBal0051833 Tm2[DeltaBgl+R]   Drosophila melanogaster
FBal0051834 Tm2[Delta-790]   Drosophila melanogaster
FBal0051835 Tm2[Delta-452]   Drosophila melanogaster
FBal0051836 Tm2[Delta-374-146]   Drosophila melanogaster
FBal0051837 Tm2[+tDelta-2500]   Drosophila melanogaster
FBal0051838 Tm2[Delta-210-146]   Drosophila melanogaster
FBal0051839 Tm2[Delta-194-146]   Drosophila melanogaster
FBal0051840 Tm2[Delta-1900]   Drosophila melanogaster
FBal0051841 Tm2[Delta-146]   Drosophila melanogaster
FBal0032025 Tm2[J8]   Drosophila melanogaster
FBal0045203 Tm2[gs]   Drosophila melanogaster
FBal0123972 Tm2[DL2]   Drosophila melanogaster
FBal0016896 Tm2[5]   Drosophila melanogaster
FBal0060550 Tm2[D53]   Drosophila melanogaster
FBal0061572 Tm2[S2]   Drosophila melanogaster
FBal0061573 Tm2[L2]   Drosophila melanogaster
FBal0032024 Tm2[C10] loss of function allele Drosophila melanogaster
FBal0208797 Tm2[GD11445]   Drosophila melanogaster
FBal0279262 Tm2[HMS02260]   Drosophila melanogaster
FBal0237341 Tm2[KK111307]   Drosophila melanogaster

278 Clones

Secondary Identifier DB identifier
AT18234 FBcl0041055
EK255653 FBcl0053448
EK249345 FBcl0053604
EK253131 FBcl0059778
EK302909 FBcl0061324
EK093318 FBcl0061532
EK223015 FBcl0061648
GH08062 FBcl0127937
GH21558 FBcl0128145
GH26446 FBcl0129047
GH09826 FBcl0129361
GH06175 FBcl0129617
GH08826 FBcl0129703
GM03004 FBcl0143430
GM09009 FBcl0143449
GM10918 FBcl0143455
GM09061 FBcl0143460
GM03017 FBcl0143475
GM02038 FBcl0143493
GM04137 FBcl0143516
GM15310 FBcl0148143
GM24429 FBcl0148144
GM21351 FBcl0148171
HL01145 FBcl0150273
HL04820 FBcl0150323
LD07793 FBcl0160023
LD06602 FBcl0160251
LP08931 FBcl0180710
LP07312 FBcl0185684
LP06317 FBcl0188166

10 Exons

DB identifier Symbol
FBgn0004117:1 Tm2:1
FBgn0004117:6 Tm2:6
FBgn0004117:7 Tm2:7
FBgn0004117:9 Tm2:9
FBgn0004117:5 Tm2:5
FBgn0004117:10 Tm2:10
FBgn0004117:2 Tm2:2
FBgn0004117:8 Tm2:8
FBgn0004117:3 Tm2:3
FBgn0004117:4 Tm2:4

5 Transcripts

DB identifier Gene
FBtr0083078 Tm2
FBtr0083079 Tm2
FBtr0083080 Tm2
FBtr0333920 Tm2
FBtr0339530 Tm2

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083078-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0083079-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0083080-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333920-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339530-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083078-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083079-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083080-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333920-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339530-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41853 NCBI Entrez Gene identifiers FBgn0004117
66917 BioGRID FBgn0004117

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 508.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 687.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 280.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 279.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 183.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 579.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 281.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 216.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 315.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 187.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 374.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 304.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 365.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 145.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 383.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 556.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 352.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 635.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 365.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 180.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 210.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 451.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 639.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 389.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 324.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 290.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 367.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 319.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 207.0
FBgn0004117 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 282.0

10 Introns

DB identifier
Organism . Name
intron_FBgn0004117:4_FBgn0004117:6 Drosophila melanogaster
intron_FBgn0004117:6_FBgn0004117:7 Drosophila melanogaster
intron_FBgn0004117:7_FBgn0004117:9 Drosophila melanogaster
intron_FBgn0004117:1_FBgn0004117:6 Drosophila melanogaster
intron_FBgn0004117:5_FBgn0004117:6 Drosophila melanogaster
intron_FBgn0004117:7_FBgn0004117:10 Drosophila melanogaster
intron_FBgn0004117:2_FBgn0004117:6 Drosophila melanogaster
intron_FBgn0004117:7_FBgn0004117:8 Drosophila melanogaster
intron_FBgn0004117:8_FBgn0004117:10 Drosophila melanogaster
intron_FBgn0004117:3_FBgn0004117:6 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Tm2 none 0.724901745   19067489
Lipid storage Tm2 none 1.650428565   19067489
Cell size and cell-cycle regulation (1) Tm2 none sp   16496002
C. trachomatis infection Tm2 C. trachomatis infection down np   18369471
Muscle morphogenesis and function (1) Tm2 Lethal np   20220848
Muscle morphogenesis and function (1) Tm2 Lethal np   20220848
Muscle morphogenesis and function (3) Tm2 Spotty (discontinuous) Z-line np   20220848
Heat nociception (1) Tm2 none -0.02   21074052
Heart development and function (1) Tm2 none 1   20371351
Serratia marcescens infection (1) Tm2 none 0.323232323232323   19520911
Serratia marcescens infection (1) Tm2 none 0.479166666666666   19520911
Serratia marcescens infection (1) Tm2 none 0.171428571428571   19520911
Notch pathway regulation (4) Tm2 none 0   19363474
Notch pathway regulation (4) Tm2 Bristle morphology defects, notum malformation death sp   19363474
Adiposity regulation (1) Tm2 none 0.001   20074523
Adiposity regulation (1) Tm2 none 0.097   20074523
Adiposity regulation (1) Tm2 none 0.581   20074523
Hippo pathway regulation Tm2 none -1.07   23263283
Muscle development and maintenance Tm2 Embryo lethal sp  
Muscle maintenance Tm2 none sp  
Glycosylation regulation (1) Tm2 none sp   21203496

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