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Gene : alphaCop D. melanogaster

DB identifier  ? FBgn0025725 Secondary Identifier  ? CG7961
Name  ? alpha-coatomer protein Source  FlyBase
  • synonyms:
  • FBgn0025725,
  • coatomer I,
  • CG7961,
  • alphaCOP,
  • alpha-COP,
  • FBan0007961,
  • COPI alpha subunit

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5 Alleles

DB identifier Symbol Allele Class Organism
FBal0245311 alphaCop[HM04008]   Drosophila melanogaster
FBal0162873 alphaCop[EY09064]   Drosophila melanogaster
FBal0263283 alphaCop[HMS01272]   Drosophila melanogaster
FBal0287521 alphaCop[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0198546 alphaCop[GD12332]   Drosophila melanogaster

97 Clones

Secondary Identifier DB identifier
EK291043 FBcl0031158
EK227159 FBcl0031232
AT07542 FBcl0014879
AT04048 FBcl0014911
AT29394 FBcl0014915
AT14693 FBcl0014919
AT06936 FBcl0014923
AT07301 FBcl0014925
EK062248 FBcl0076488
EK205545 FBcl0077002
EK126264 FBcl0077072
EK249547 FBcl0077520
EK101960 FBcl0077610
EP16202 FBcl0077847
EK091245 FBcl0078076
EK015941 FBcl0078360
GH17773 FBcl0123315
GH21307 FBcl0123319
GH07071 FBcl0123341
GH26487 FBcl0123395
GH05720 FBcl0132229
GH13925 FBcl0133339
GH23550 FBcl0133403
GH04856 FBcl0133553
GM01503 FBcl0138195
GM01505 FBcl0138387
GM10737 FBcl0139579
GM18359 FBcl0145043
HL02203 FBcl0149951
LD46584 FBcl0172831

4 Exons

DB identifier Symbol
FBgn0025725:4 alphaCop:4
FBgn0025725:2 alphaCop:2
FBgn0025725:1 alphaCop:1
FBgn0025725:3 alphaCop:3

2 Transcripts

DB identifier Gene
FBtr0072811 alphaCop
FBtr0072812 alphaCop

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072811-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072812-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072811-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072812-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38199 NCBI Entrez Gene identifiers FBgn0025725
63733 BioGRID FBgn0025725

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1882.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1974.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1240.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2554.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2248.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 732.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1681.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1595.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1028.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2016.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1673.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1136.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1800.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1627.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1920.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1085.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1620.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1549.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1443.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1385.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2498.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2225.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1486.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1676.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1510.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1152.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 559.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 732.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 793.0
FBgn0025725 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 985.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0025725:4_FBgn0025725:2 Drosophila melanogaster
intron_FBgn0025725:2_FBgn0025725:1 Drosophila melanogaster
intron_FBgn0025725:3_FBgn0025725:1 Drosophila melanogaster

40 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage alphaCop Increased lipid droplet area 4.79558231   19067489
Lipid storage alphaCop Increased lipid droplet area 9.060256339   19067489
Chlamydia caviae infection alphaCop Decreased Chlamydia caviae infection np   17967059
ERK signaling alphaCop ERK activation increased strong   17086199
Drosophila C virus infection alphaCop Drosophila C virus replication down np   17040126
Intracellular Listeria monocytogenes infection alphaCop Decreased GFP protein expression strong   16020693
L. monocytogenes infection alphaCop Fewer infected cells, less vacuolar escape ***   16157870
Hedgehog signaling alphaCop Decreased Hedgehog reporter activity -3.01   16311596
Mycobacterial infection (1) - M. fortuitum infection alphaCop Decreased M. fortuitum intracellular infection 10.1 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis alphaCop Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) alphaCop Decreased G1 DNA content, increased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (2) alphaCop none 1.317   16496002
Cell size and cell-cycle regulation (3) alphaCop none 465   16496002
Cell size and cell-cycle regulation (4) alphaCop Increased number of mitotic cells 0.6   16496002
Candida albicans phagocytosis (1) alphaCop Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) alphaCop Decreased Escherichia coli phagocytosis 22   16336044
Candida albicans phagocytosis (3) alphaCop Decreased latex beads phagocytosis 25   16336044
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) alphaCop Decreased human CD4 surface protein expression CD4 after human immunodeficiency virus Type 1 Nef (HIV-1 Nef) stimulation 1.44   17267500
Brucella melitensis infection alphaCop Decreased viability np   18654626
Lipid storage alphaCop Normal/larger sized lipid droplets, more dispersed strong   18408709
Mutant human huntingtin aggregation alphaCop Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) alphaCop Lethal np   20220848
Muscle morphogenesis and function (1) alphaCop Lethal np   20220848
Heart development and function (1) alphaCop Embryonic lethal or no offspring 0   20371351
Serratia marcescens infection (1) alphaCop Decreased viability after Serratia marcescens infection -1.82432432432432   19520911
Serratia marcescens infection (2) alphaCop Decreased viability after Serratia marcescens infection sp   19520911
Serratia marcescens infection (4) alphaCop none sp   19520911
Notch pathway regulation (4) alphaCop Completely lethal (before pupal) sp   19363474
Notch pathway regulation (4) alphaCop Completely lethal (before pupal) sp   19363474
Hh pathway regulation alphaCop Downregulation of Hh pathway -0.273368881017403   17903264

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