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Gene : Ubi-p63E D. melanogaster

DB identifier  ? FBgn0003943 Secondary Identifier  ? CG11624
Name  ? Ubiquitin-63E Source  FlyBase
  • synonyms:
  • DmUb,
  • Ubi-p,
  • Ubip63E,
  • CG11624-RB,
  • CG11624-PB,
  • CG11624-RC,
  • Ubiquitin,
  • DmUbi-p63E,
  • Ubiquitin-polymeric,
  • polyubiquitin,
  • ubi,
  • CG11624-PA,
  • FBgn0003943,
  • FBan0011624,
  • Ubi63E,
  • Ubp,
  • CG11624-RA,
  • Ub,
  • CG11624,
  • Ubip,
  • Ubiq,
  • Ubi-P63e,
  • Ubi63p

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11 Alleles

DB identifier Symbol Allele Class Organism
FBal0257182 Ubi-p63E[HMS00284]   Drosophila melanogaster
FBal0181104 Ubi-p63E[e03111]   Drosophila melanogaster
FBal0181105 Ubi-p63E[e02712]   Drosophila melanogaster
FBal0181106 Ubi-p63E[c04861]   Drosophila melanogaster
FBal0159570 Ubi-p63E[EY07341]   Drosophila melanogaster
FBal0147334 Ubi-p63E[unspecified]   Drosophila melanogaster
FBal0135769 Ubi-p63E[dsRNA.cRa]   Drosophila melanogaster
FBal0197697 Ubi-p63E[dsRNA.cMa]   Drosophila melanogaster
FBal0101526 Ubi-p63E[hs.T:Ivir\HA1]   Drosophila melanogaster
FBal0141333 Ubi-p63E[MtnA.T:Ivir\HA1]   Drosophila melanogaster
FBal0236232 Ubi-p63E[KK109327]   Drosophila melanogaster

89 Clones

Secondary Identifier DB identifier
ESG0115d.B21_G04 FBcl0001771
ESG0119a.B21_H09 FBcl0002205
ESG0118b.B21_G08 FBcl0002511
ESG017c.E21.1_B07 FBcl0005285
ESG014b.E21_H01 FBcl0010021
bs46c07 FBcl0047201
bs61e05 FBcl0047713
bs57g01 FBcl0047715
bs03e12 FBcl0047717
bs80b10 FBcl0047719
bs48g04 FBcl0047723
bs25b12 FBcl0047725
bs20h11 FBcl0047729
bs17c04 FBcl0047731
bs70b07 FBcl0047735
bs73d05 FBcl0047739
bs61g12 FBcl0047741
bs60h08 FBcl0047743
bs54h05 FBcl0047745
bs85h05 FBcl0047747
bs85c09 FBcl0047749
bs23e05 FBcl0047751
bs37f03 FBcl0047753
bs26h08 FBcl0047757
bs22g08 FBcl0047759
bs86e08 FBcl0047761
EK175461 FBcl0086438
GH20426 FBcl0107495
GH27078 FBcl0107581
GH07884 FBcl0107589

7 Exons

DB identifier Symbol
FBgn0003943:7 Ubi-p63E:7
FBgn0003943:2 Ubi-p63E:2
FBgn0003943:3 Ubi-p63E:3
FBgn0003943:1 Ubi-p63E:1
FBgn0003943:6 Ubi-p63E:6
FBgn0003943:5 Ubi-p63E:5
FBgn0003943:4 Ubi-p63E:4

4 Transcripts

DB identifier Gene
FBtr0073178 Ubi-p63E
FBtr0073179 Ubi-p63E
FBtr0073177 Ubi-p63E
FBtr0333142 Ubi-p63E

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073177-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073179-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0073178-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333142-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073177-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073179-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073178-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333142-3-prime-utr Drosophila melanogaster

Interactions

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Other

187 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38456 NCBI Entrez Gene identifiers FBgn0003943
63944 BioGRID FBgn0003943

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3102.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3572.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 14126.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2505.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2706.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 11209.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 9805.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 12221.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 14853.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 10445.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 7731.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 8647.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 8577.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 13402.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 11720.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 11053.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 7566.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 7694.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 11569.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3179.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 12494.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 11934.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 9343.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 8107.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 6565.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 12045.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 8098.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 7648.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 10215.0
FBgn0003943 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 9629.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0003943:6_FBgn0003943:5 Drosophila melanogaster
intron_FBgn0003943:5_FBgn0003943:1 Drosophila melanogaster
intron_FBgn0003943:3_FBgn0003943:1 Drosophila melanogaster
intron_FBgn0003943:7_FBgn0003943:2 Drosophila melanogaster
intron_FBgn0003943:4_FBgn0003943:1 Drosophila melanogaster

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Ubi-p63E none -0.280638698   19067489
Lipid storage Ubi-p63E none -1.882014772   19067489
Chlamydia caviae infection Ubi-p63E Decreased Chlamydia caviae infection np   17967059
Drosophila C virus infection Ubi-p63E Drosophila C virus replication down np   17040126
E. coli / S. aureus infection Ubi-p63E Cell death np   11912489
Cytokinesis regulation Ubi-p63E Binucleate cells with decreased viability weak   15547975
Intracellular Listeria monocytogenes infection Ubi-p63E Decreased GFP protein expression strong   16020693
Hedgehog signaling Ubi-p63E Decreased Hedgehog reporter activity -3.8   16311596
Hedgehog signaling Ubi-p63E Decreased Hedgehog reporter activity -4.44   16311596
Mycobacterial infection (1) - M. fortuitum infection Ubi-p63E Decreased M. fortuitum intracellular infection 11.8 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Ubi-p63E Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) Ubi-p63E Decreased G1 DNA content, decreased G1 cell size, decreased viability, increased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) Ubi-p63E Decreased viability 0.28   16496002
Cell size and cell-cycle regulation (3) Ubi-p63E Decreased cell number 26   16496002
Cell size and cell-cycle regulation (4) Ubi-p63E none below threshold   16496002
Candida albicans phagocytosis (1) Ubi-p63E Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Ubi-p63E Decreased Escherichia coli phagocytosis 24   16336044
Candida albicans phagocytosis (3) Ubi-p63E Decreased latex beads phagocytosis 33   16336044
Mutant human huntingtin aggregation Ubi-p63E Decreased mutant human huntingtin aggregation <= -2   19789644
RTK-Ras-ERK pathway regulation (1) Ubi-p63E none -0.2 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Ubi-p63E Decreased ERK phosphorylation after EGF stimulation -7.25 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Ubi-p63E Decreased ERK phosphorylation after sSpitz and EGF stimulation -7.57 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Ubi-p63E Decreased ERK phosphorylation after sSpitz and EGF stimulation -5.57 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Ubi-p63E none 0.38   23263283

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