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Gene : gfzf D. melanogaster

DB identifier  ? FBgn0250732 Secondary Identifier  ? CG33546
Name  ? GST-containing FLYWCH zinc-finger protein Source  FlyBase
  • synonyms:
  • FBan0031492,
  • FBgn0037479,
  • FBgn0053546,
  • FBpp0081125,
  • FBgn0250732,
  • FBgn0002305,
  • FBtr0081607,
  • dGFZF,
  • FBgn0051492,
  • CG31329,
  • l(3)84Cc,
  • CG10065,
  • FBan0031329,
  • Su(Kpn),
  • Suppressor of Killer of prune,
  • FBgn0051329,
  • CG31492,
  • GFZF,
  • FBtr0081608,
  • CG33546,
  • lethal (3) 84Cc,
  • FBpp0081126

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32 Alleles

DB identifier Symbol Allele Class Organism
FBal0010120 gfzf[2]   Drosophila melanogaster
FBal0010121 gfzf[3]   Drosophila melanogaster
FBal0010119 gfzf[1]   Drosophila melanogaster
FBal0248348 gfzf[6a27]   Drosophila melanogaster
FBal0159189 gfzf[EY08448]   Drosophila melanogaster
FBal0286052 gfzf[MI08697]   Drosophila melanogaster
FBal0175676 gfzf[MtnA.PD]   Drosophila melanogaster
FBal0043780 gfzf[r1]   Drosophila melanogaster
FBal0175677 gfzf[DeltaN108.MtnA]   Drosophila melanogaster
FBal0248155 gfzf[HMS00394]   Drosophila melanogaster
FBal0209634 gfzf[GD10231]   Drosophila melanogaster
FBal0209635 gfzf[GD10273]   Drosophila melanogaster
FBal0212661 gfzf[Su(Kpn)1] loss of function allele Drosophila melanogaster
FBal0212662 gfzf[Su(Kpn)2] loss of function allele Drosophila melanogaster
FBal0212663 gfzf[Su(Kpn)3] loss of function allele Drosophila melanogaster
FBal0212664 gfzf[AB621]   Drosophila melanogaster
FBal0212665 gfzf[AP320]   Drosophila melanogaster
FBal0212666 gfzf[AP434]   Drosophila melanogaster
FBal0212667 gfzf[AV739]   Drosophila melanogaster
FBal0212668 gfzf[BS304]   Drosophila melanogaster
FBal0212669 gfzf[BU640]   Drosophila melanogaster
FBal0212670 gfzf[BW914]   Drosophila melanogaster
FBal0212671 gfzf[BX123]   Drosophila melanogaster
FBal0212672 gfzf[CK438]   Drosophila melanogaster
FBal0212673 gfzf[CL1027]   Drosophila melanogaster
FBal0212674 gfzf[CU338]   Drosophila melanogaster
FBal0212675 gfzf[CX322]   Drosophila melanogaster
FBal0212676 gfzf[CZ811]   Drosophila melanogaster
FBal0212677 gfzf[DC727]   Drosophila melanogaster
FBal0212678 gfzf[DC806]   Drosophila melanogaster

58 Clones

Secondary Identifier DB identifier
DPiM_RE40740 FBcl0741868
EK163026 FBcl0018108
EK296001 FBcl0018146
EK258404 FBcl0018282
EK306415 FBcl0018302
EK106346 FBcl0018322
EK250226 FBcl0018374
AT30556 FBcl0045613
EP08055 FBcl0090111
EP16757 FBcl0090115
EP15126 FBcl0090121
EP06853 FBcl0090123
GH03382 FBcl0125495
GM05862 FBcl0143779
LD10915 FBcl0159147
LD12164 FBcl0159161
LD15894 FBcl0159170
LD16729 FBcl0159177
LD19120 FBcl0159183
LD01579 FBcl0159193
LD46780 FBcl0173825
LD30165 FBcl0173874
LD31389 FBcl0173880
LD28622 FBcl0173882
LD29031 FBcl0173899
LD46335 FBcl0173900
LD29809 FBcl0173901
LP09753 FBcl0187595
LP08001 FBcl0187597
RE17582 FBcl0223727

6 Exons

DB identifier Symbol
FBgn0250732:6 gfzf:6
FBgn0250732:5 gfzf:5
FBgn0250732:3 gfzf:3
FBgn0250732:1 gfzf:1
FBgn0250732:4 gfzf:4
FBgn0250732:2 gfzf:2

3 Transcripts

DB identifier Gene
FBtr0091512 gfzf
FBtr0334671 gfzf
FBtr0114531 gfzf

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0091512-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0114531-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334671-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0091512-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0114531-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334671-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40858 NCBI Entrez Gene identifiers FBgn0250732
66053 BioGRID FBgn0250732

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 738.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 835.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 636.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 656.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 713.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 389.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 658.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 766.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 415.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 756.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 713.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 543.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 679.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 675.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 903.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 630.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 676.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 901.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 853.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 557.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1013.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 727.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 635.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 590.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 665.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2049.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1728.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1479.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1117.0
FBgn0250732 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 969.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0250732:6_FBgn0250732:5 Drosophila melanogaster
intron_FBgn0250732:5_FBgn0250732:3 Drosophila melanogaster
intron_FBgn0250732:3_FBgn0250732:1 Drosophila melanogaster
intron_FBgn0250732:4_FBgn0250732:3 Drosophila melanogaster
intron_FBgn0250732:3_FBgn0250732:2 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation gfzf Decreased cell size -3.02   19216764
Lipid storage gfzf none 0.007289833   19067489
Lipid storage gfzf none 0.288533825   19067489
Lipid storage gfzf none -0.331952073   19067489
Lipid storage gfzf none -0.485391039   19067489
E2F signaling gfzf E2F signaling upregulated np   17517653
ERK signaling gfzf ERK activation reduced weak   17086199
Combinatorial effect with methyl methanesulphonate (1) gfzf Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) gfzf Weak flyer np   20220848
Muscle morphogenesis and function (1) gfzf Lethal np   20220848
Muscle morphogenesis and function (1) gfzf Lethal np   20220848
Heat nociception (1) gfzf Developmentally lethal 0   21074052
Heat nociception (1) gfzf none -1.17   21074052
Notch pathway regulation (4) gfzf Notum malformation death 9   19363474
Notch pathway regulation (4) gfzf Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) gfzf Notum malformation death 9   19363474
Notch pathway regulation (4) gfzf Notum malformation death 8   19363474
G2-M DNA damage checkpoint regulation (2) gfzf Increased histone H3 phosphorylation with doxorubicin 23.01 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) gfzf Increased histone H3 phosphorylation with etoposide 51.91 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) gfzf none 26.74 X-ray exposure 21205937
G2-M DNA damage checkpoint regulation (2) gfzf Increased histone H3 phosphorylation with bleocin 16.46 with bleocin 21205937
Self-renewal and differentiation in neural stem cells gfzf GFP aggregates number, GFP aggregates size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underproliferation, lethal sp   21549331
Self-renewal and differentiation in neural stem cells gfzf GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with larger neuroblast cell size, neuroblast underprolifer sp   21549331
Self-renewal and differentiation in neural stem cells gfzf GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underprolifer sp   21549331
RTK-Ras-ERK pathway regulation (1) gfzf none -0.03 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) gfzf none -0.76 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) gfzf none -0.28 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) gfzf none 0.53 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation gfzf none 1.77   23263283
Hippo pathway regulation gfzf none 0.46   23263283

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