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Gene : wts D. melanogaster

DB identifier  ? FBgn0011739 Secondary Identifier  ? CG12072
Name  ? warts Source  FlyBase
  • synonyms:
  • WTS/LATS,
  • MENE (3R)-G,
  • wart,
  • Warts,
  • dmLATS,
  • FBgn0013549,
  • Lats/Warts,
  • large tumor supressor,
  • FBgn0011739,
  • lts,
  • miracle-gro,
  • Warts/Lats,
  • warts/D-lats,
  • FBan0012072,
  • LATS1,
  • LATS,
  • Dlats,
  • l(3)100Aa,
  • Wts,
  • warts/large tumour suppressor,
  • CG12072,
  • large tumor suppressor

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114 Alleles

DB identifier Symbol Allele Class Organism
FBal0177118 wts[DG12310]   Drosophila melanogaster
FBal0277189 wts[MI05605]   Drosophila melanogaster
FBal0177115 wts[d03508]   Drosophila melanogaster
FBal0177114 wts[f00653]   Drosophila melanogaster
FBal0177116 wts[c02680]   Drosophila melanogaster
FBal0044486 wts[P10]   Drosophila melanogaster
FBal0044513 wts[P509-19] wild-type allele Drosophila melanogaster
FBal0044485 wts[P1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0044487 wts[P11]   Drosophila melanogaster
FBal0044488 wts[P12]   Drosophila melanogaster
FBal0044489 wts[P13]   Drosophila melanogaster
FBal0044491 wts[P15]   Drosophila melanogaster
FBal0044492 wts[P16]   Drosophila melanogaster
FBal0044493 wts[P17]   Drosophila melanogaster
FBal0044494 wts[P18]   Drosophila melanogaster
FBal0044495 wts[P19]   Drosophila melanogaster
FBal0044496 wts[P2]   Drosophila melanogaster
FBal0044497 wts[P20]   Drosophila melanogaster
FBal0044498 wts[P21]   Drosophila melanogaster
FBal0044499 wts[P22]   Drosophila melanogaster
FBal0044500 wts[P23]   Drosophila melanogaster
FBal0044501 wts[P24]   Drosophila melanogaster
FBal0044502 wts[P25]   Drosophila melanogaster
FBal0044503 wts[P26]   Drosophila melanogaster
FBal0044504 wts[P27]   Drosophila melanogaster
FBal0044505 wts[P28]   Drosophila melanogaster
FBal0044506 wts[P29]   Drosophila melanogaster
FBal0044507 wts[P3]   Drosophila melanogaster
FBal0044508 wts[P30]   Drosophila melanogaster
FBal0044509 wts[P31]   Drosophila melanogaster

22 Clones

Secondary Identifier DB identifier
EK112464 FBcl0007184
GH28053 FBcl0108051
EK139603 FBcl0138906
EK051224 FBcl0139106
EK226063 FBcl0139262
EK049949 FBcl0140744
EK092912 FBcl0140882
EK093149 FBcl0141204
SD26853 FBcl0290222
SD19495 FBcl0290223
EC055356 FBcl0300584
EC055313 FBcl0300585
EC055042 FBcl0300586
EC053975 FBcl0300587
CK01.121D.E10 FBcl0427983
FGM220H11 FBcl0390693
CK01.63C.F11 FBcl0427957
CK01.62A.E2 FBcl0427976
CK01.121C.C7 FBcl0427979
CK01.21A.F5 FBcl0467765
102479 FBcl0427966
11933 FBcl0467778

8 Exons

DB identifier Symbol
FBgn0011739:8 wts:8
FBgn0011739:7 wts:7
FBgn0011739:6 wts:6
FBgn0011739:5 wts:5
FBgn0011739:4 wts:4
FBgn0011739:3 wts:3
FBgn0011739:2 wts:2
FBgn0011739:1 wts:1

1 Transcripts

DB identifier Gene
FBtr0085720 wts

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0085720-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085720-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43651 NCBI Entrez Gene identifiers FBgn0011739
68502 BioGRID FBgn0011739

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 923.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 565.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 442.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 265.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 489.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1197.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 582.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 916.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1007.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1472.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1553.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 530.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 643.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1470.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 639.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 712.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1172.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 709.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 507.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 660.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 916.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 821.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 449.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1735.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 840.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2087.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 854.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1217.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1045.0
FBgn0011739 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 820.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0011739:8_FBgn0011739:7 Drosophila melanogaster
intron_FBgn0011739:7_FBgn0011739:6 Drosophila melanogaster
intron_FBgn0011739:6_FBgn0011739:5 Drosophila melanogaster
intron_FBgn0011739:5_FBgn0011739:4 Drosophila melanogaster
intron_FBgn0011739:4_FBgn0011739:3 Drosophila melanogaster
intron_FBgn0011739:3_FBgn0011739:2 Drosophila melanogaster
intron_FBgn0011739:2_FBgn0011739:1 Drosophila melanogaster

37 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage wts none -0.210911332   19067489
Lipid storage wts none 0.374395735   19067489
Lipid storage wts none 2.82791102   19067489
Lipid storage wts none -0.799617567   19067489
Cell cycle regulation (1) wts Increased G1 DNA content sp   15616552
Cell cycle regulation (2) wts Increased G1 DNA content, increased cell size np   15616552
Wnt signaling wts Increased Wnt reporter activity 7.8   15817814
Constitutive protein secretion and Golgi organization (1) wts Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) wts none sp   16496002
Cell size and cell-cycle regulation (1) wts none sp   16496002
Ca2+ channel regulation wts Decreased Ca2+ influx 2   16645049
Combinatorial effect with methyl methanesulphonate (1) wts Synthetic lethal with methyl methanesulphonate sp   19543366
Combinatorial effect with methyl methanesulphonate (2) wts none sp   19543366
Mutant human huntingtin aggregation wts Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) wts none np   20220848
Heat nociception (1) wts none -1.17   21074052
Heart development and function (1) wts none 1   20371351
Serratia marcescens infection (1) wts none -0.314606741573033   19520911
Notch pathway regulation (4) wts none 0   19363474
Notch pathway regulation (4) wts Colour defects, notum malformation migration, overproliferation sp   19363474
Adiposity regulation (1) wts none -0.526   20074523
Blood cell homeostasis regulation (1) wts none np   20540764
Blood cell homeostasis regulation (2) wts Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) wts none 0   20540764
Blood cell homeostasis regulation (4) wts none 0   20540764
Blood cell homeostasis regulation (5) wts none 0   20540764
S2 cell spreading wts none np   21041442
Actin organization and cell morphology (1) wts none np   19265526
Actin organization and cell morphology (2) wts Altered cell morphology np   19265526
Actin organization and cell morphology (3) wts Altered cell morphology np   19265526

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