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Gene : Mkp3 D. melanogaster

DB identifier  ? FBgn0036844 Secondary Identifier  ? CG14080
Name  ? Mitogen-activated protein kinase phosphatase 3 Source  FlyBase
  • synonyms:
  • FBan0014080,
  • MKP-like,
  • Dmkp3,
  • MAPK phosphatase 3,
  • unnamed,
  • FBgn0036845,
  • MKP3,
  • DMKP-3,
  • CG14081,
  • FBgn0036844,
  • CG14080,
  • MKP-3-like,
  • MAP Kinase Phosphatase 3,
  • Drosophila MKP-3,
  • mkp-3,
  • MAPK phosphatase-3

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50 Alleles

DB identifier Symbol Allele Class Organism
FBal0156237 Mkp3[EY02009a]   Drosophila melanogaster
FBal0182702 Mkp3[d09294]   Drosophila melanogaster
FBal0182705 Mkp3[c05137]   Drosophila melanogaster
FBal0182706 Mkp3[c02582]   Drosophila melanogaster
FBal0182703 Mkp3[d08832]   Drosophila melanogaster
FBal0260387 Mkp3[MI02654]   Drosophila melanogaster
FBal0182704 Mkp3[d01703]   Drosophila melanogaster
FBal0182699 Mkp3[f05234]   Drosophila melanogaster
FBal0182700 Mkp3[f03498]   Drosophila melanogaster
FBal0182701 Mkp3[e01205]   Drosophila melanogaster
FBal0152418 Mkp3[8]   Drosophila melanogaster
FBal0152419 Mkp3[7]   Drosophila melanogaster
FBal0152428 Mkp3[10]   Drosophila melanogaster
FBal0152420 Mkp3[6]   Drosophila melanogaster
FBal0152422 Mkp3[5]   Drosophila melanogaster
FBal0152417 Mkp3[9]   Drosophila melanogaster
FBal0152427 Mkp3[11]   Drosophila melanogaster
FBal0152423 Mkp3[4] loss of function allele Drosophila melanogaster
FBal0152424 Mkp3[3] loss of function allele Drosophila melanogaster
FBal0152425 Mkp3[2] loss of function allele Drosophila melanogaster
FBal0152426 Mkp3[1] loss of function allele Drosophila melanogaster
FBal0213200 Mkp3[NP3460]   Drosophila melanogaster
FBal0213201 Mkp3[GS.S]   Drosophila melanogaster
FBal0213202 Mkp3[GS160]   Drosophila melanogaster
FBal0213203 Mkp3[M76-M] loss of function allele Drosophila melanogaster
FBal0152415 Mkp3[hs.sev]   Drosophila melanogaster
FBal0135970 Mkp3[CA.Act5C]   Drosophila melanogaster
FBal0135969 Mkp3[CA.RR.Act5C]   Drosophila melanogaster
FBal0135966 Mkp3[RR.Act5C]   Drosophila melanogaster
FBal0240671 Mkp3[P3]   Drosophila melanogaster

52 Clones

Secondary Identifier DB identifier
DPiM_RE08706 FBcl0740939
GH27844 FBcl0109887
EK262317 FBcl0137738
EK119918 FBcl0137740
EK227135 FBcl0137742
EK258430 FBcl0137744
EK252615 FBcl0137748
EK175142 FBcl0137750
EK075501 FBcl0137752
EK075505 FBcl0137754
EK259510 FBcl0137756
EK135452 FBcl0137868
EK077402 FBcl0137872
EK206546 FBcl0137874
EK086021 FBcl0137876
EK293002 FBcl0137886
EK273413 FBcl0137888
GM13896 FBcl0145691
LD02618 FBcl0153444
RE37942 FBcl0201884
RE71634 FBcl0201893
RE64291 FBcl0201904
RE08706 FBcl0201905
RE60842 FBcl0201909
RE60593 FBcl0201911
RE07150 FBcl0201912
RE19640 FBcl0201916
SD06439 FBcl0282267
SD27763 FBcl0282313
EC052231 FBcl0302654

8 Exons

DB identifier Symbol
FBgn0036844:8 Mkp3:8
FBgn0036844:6 Mkp3:6
FBgn0036844:5 Mkp3:5
FBgn0036844:4 Mkp3:4
FBgn0036844:2 Mkp3:2
FBgn0036844:3 Mkp3:3
FBgn0036844:7 Mkp3:7
FBgn0036844:1 Mkp3:1

4 Transcripts

DB identifier Gene
FBtr0075036 Mkp3
FBtr0075035 Mkp3
FBtr0333220 Mkp3
FBtr0330089 Mkp3

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075035-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075036-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330089-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333220-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075035-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075036-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330089-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333220-3-prime-utr Drosophila melanogaster

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1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40081 NCBI Entrez Gene identifiers FBgn0036844

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2568.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2064.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2836.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 934.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2032.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 4301.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3908.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2231.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2435.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3503.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 3227.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 2067.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 3024.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2055.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 5889.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2638.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3701.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2342.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 3936.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 4388.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 5751.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3107.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1262.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2234.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2285.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3275.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2162.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1237.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1295.0
FBgn0036844 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1272.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0036844:7_FBgn0036844:6 Drosophila melanogaster
intron_FBgn0036844:6_FBgn0036844:5 Drosophila melanogaster
intron_FBgn0036844:5_FBgn0036844:4 Drosophila melanogaster
intron_FBgn0036844:4_FBgn0036844:2 Drosophila melanogaster
intron_FBgn0036844:8_FBgn0036844:6 Drosophila melanogaster
intron_FBgn0036844:4_FBgn0036844:3 Drosophila melanogaster
intron_FBgn0036844:4_FBgn0036844:1 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Mkp3 none -2.395043582   19067489
Lipid storage Mkp3 none 1.664124844   19067489
Lipid storage Mkp3 none -0.091325544   19067489
Lipid storage Mkp3 none 1.181595746   19067489
Lipid storage Mkp3 none 0.535882016   19067489
Cell size and cell-cycle regulation (1) Mkp3 none sp   16496002
Cell size and cell-cycle regulation (1) Mkp3 none sp   16496002
Cell size and cell-cycle regulation (1) Mkp3 none sp   16496002
Muscle morphogenesis and function (1) Mkp3 none np   20220848
Heat nociception (1) Mkp3 none -1.17   21074052
Heart development and function (1) Mkp3 none 1   20371351
Serratia marcescens infection (1) Mkp3 none 0.544117647058823   19520911
Notch pathway regulation (4) Mkp3 Notum malformation death 1   19363474
Notch pathway regulation (4) Mkp3 none 0   19363474
PGN-induced dJNK phosphorylation Mkp3 Decreased P-JNK protein expression with PGN -2.38 15 min PGN induction 19893628
Notch pathway regulation (1) Mkp3 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Mkp3 none np C96-GAL4 20493818
Notch pathway regulation (2) Mkp3 Upregulation of Notch pathway; adult wing veins: thinner; adult wing posterior compartment: smaller, opaque; wing disc NRE:EGFP: up, broader sp en-GAL4 20493818
Notch pathway regulation (3) Mkp3 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) Mkp3 none -0.28   20074523
Vaccinia virus infection Mkp3 none sp   20585561
RTK-Ras-ERK pathway regulation (1) Mkp3 Decreased ERK phosphorylation after EGF stimulation -1.73 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Mkp3 none -0.34 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Mkp3 none -0.13 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Mkp3 Decreased ERK phosphorylation after sSpitz and EGF stimulation -1.58 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Mkp3 none -0.21   23263283

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